Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human

Nowatari Takeshi; Murata Soichiro; Nakayama KenSano NaokiMaruyama TakehitoNozaki ReijiIkeda NaoyaFukunaga KiyoshiOhkohchi Nobuhiro

首页> 外文期刊>Hepatology research: the official journal of the Japan Society of Hepatology >Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human

【24h】

Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human

机译：鞘氨醇1-phosphate抗凋亡作用在肝脏内皮细胞和正弦在肝细胞增殖的影响旁分泌的方式在人类

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Aim: Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite released from erythrocytes and platelets, and is a potent stimulus for endothelial cell proliferation. However, the role of S1P on human liver sinusoidal endothelial cells (LSEC) remains unclear. The proliferation and inhibition of apoptosis in LSEC are involved in the promotion of liver regeneration and the suppression of liver injury after liver resection and transplantation. The aim of this study is to investigate the role of S1P on human LSEC and the interaction between S1P and LSEC in hepatocyte proliferation in vitro.

机译：目的:鞘氨醇1-phosphate (S1P)是一种生物活性鞘脂类代谢产物释放红细胞和血小板,是有效的刺激内皮细胞增殖。然而,S1P人类肝脏的作用正弦内皮细胞(LSEC)仍然存在不清楚。细胞凋亡在LSEC参与促销肝再生的抑制肝切除术后肝损伤移植。调查人类LSEC和S1P的角色在肝细胞S1P和LSEC之间的互动体外增殖。

著录项

来源
《Hepatology research: the official journal of the Japan Society of Hepatology》 |2015年第11期|1136-1145|共10页
作者
Nowatari Takeshi; Murata Soichiro; Nakayama KenSano NaokiMaruyama TakehitoNozaki ReijiIkeda NaoyaFukunaga KiyoshiOhkohchi Nobuhiro;
展开▼
作者单位

Univ Tsukuba, Dept Surg, Div Gastroenterol & Hepatobiliary Surg & Organ Tr, Tsukuba, Ibaraki;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类
关键词
Hepatocytes; Endothelial Cells; Liver RegenerationSinusoidalsphingosine 1-phosphate;

机译：肝细胞、内皮细胞、肝脏RegenerationSinusoidalsphingosine 1-phosphate;

相似文献

外文文献
中文文献

1. Interaction between Colon Cancer Cells and Human Liver Sinusoidal Endothelial Cells Promotes Liver Metastasis of Tumor Cells [J] . Li-chao SUN, Shu-ting LI, Long YU, 癌症生物学与医学（英文版） . 2011,第003期
2. Effect of Xueful Zhuyu Decoction (血府逐瘀汤) on the Function of Platelets and Human Umbilical Vein Endothelial Cell [J] . LI Yanmei, WANG Zhong, WENG Jin Chinese Journal of Integrated Traditional and Western Medicine . 2000,第4期

机译：Effect of Xueful Zhuyu Decoction (血府逐瘀汤) on the Function of Platelets and Human Umbilical Vein Endothelial Cell
3. Proteomic studies on anti-proliferating activities of adenosine and cordycepin in human cancer cell lines. [O] . 2004

机译：proteomic studies on anti-proliferating activities of adenosine and cordycepin in human cancer cell lines.

Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human

摘要

著录项

相似文献

相关主题

期刊订阅