Although recent studies of intrathecal oxytocin in humans and animals have indicated a positive analgesic effect, the potential analgesic effects of endogenous oxytocin released during breast-feeding have not been adequately investigated. The current study was undertaken to determine the analgesic impact of breastfeeding on postpartum incisional, perineal, and cramping pain.This prospective observational study enrolled 83 participants who underwent vaginal (n = 43) or scheduled cesarean delivery between August 2011 and June 2012. Eligible patients (>=18 years, American Society of Anesthesiologists physical status 1 or 2, term gestation, multiparous with previous breast-feeding experience, and Pfanenstiel incision for cesarean delivery) were approached for study enrollment 12 to 24 hours after vaginal delivery and within 24 hours of cesarean delivery.
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