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首页> 外文期刊>Heart and Lung: The Journal of Critical Care >Acute epigastric and low back pain during amiodarone infusion; is it the drug or the vehicle to blameα
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Acute epigastric and low back pain during amiodarone infusion; is it the drug or the vehicle to blameα

机译：急性上腹部和腰痛胺碘酮注入;车辆责任α

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摘要

Amiodarone is a Class III antiarrhythmic agent used for cardioversion and prevention of recurrences of atrial fibrillation. However, its use is limited due to its side-effects resulting from the drug's long-term administration. We have described acute epigastric pain following treatment with intravenous amiodarone for atrial fibrillation in a previous report. Hereby, we describe a second patient who suffered acute epigastric pain, as well as one who suffered acute low back pain. Intravenous amiodarone has been related to a series of minor and major adverse reactions, indicating other constituents of the intravenous solution as the possible cause, possibly polysorbate-80. A possible correlation between acute epigastric and low back pain after intravenous amiodarone loading is unproven; however it is of crucial importance for clinicians to be aware of this phenomenon, and especially since an acute epigastric pain is implicated in the differential diagnosis of cardiac ischemia.
机译：胺碘酮是一个第三类抗心律失常的代理用于复律法和预防房颤的复发。使用有限的由于其副作用产生从药物的长期管理。描述急性上腹痛用静脉注射胺碘酮治疗心房纤维性颤动在以前的报告。描述第二个病人遭受严重上腹部疼痛,以及遭遇的人急性腰痛。相关的一系列小和专业不良反应,说明其他成分静脉注射的解决方案是可能的可能原因,聚山梨醇酯- 80。急性上腹部和腰之间的相关性静脉注射胺碘酮加载后疼痛未经证实的;临床医生需要注意的这一现象特别是急性上腹痛涉及的鉴别诊断心脏缺血。

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