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首页> 外文期刊>Lung cancer: Journal of the International Association for the Study of Lung Cancer >Routine screening by brain magnetic resonance imaging decreased the brain metastasis rate following surgery for lung adenocarcinoma.
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Routine screening by brain magnetic resonance imaging decreased the brain metastasis rate following surgery for lung adenocarcinoma.

机译:由大脑磁共振常规筛查成像脑转移率下降为肺腺癌手术后。

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摘要

Since May 1999, the institutional guidelines of Samsung Medical Center, Seoul, Korea, have required preoperative magnetic resonance (MR) screening of the brain in all patients with lung adenocarcinoma. To investigate the brain metastasis and survival rates since the adoption of this guideline, we retrospectively reviewed the medical records of patients who underwent complete lung resection between January 1995 and December 2000. Recurrence rate, recurrence site, and survival were investigated and compared between patients with lung adenocarcinoma who underwent complete resection before May 1999, who did not undergo MR screening of the brain (non-MR group, n=160), and those after May 1999, who did receive MR screening of the brain (MR group, n=86). The brain metastasis rate was lower in the MR group than in the non-MR group (p<0.05), especially for the first 2 years. However, the recurrence rate at sites other than the brain was similar between the two groups. The 5-year survival was higher in the MR group (59%) than in the non-MR group (45%, p<0.05). Even in patients with stage I cancer, brain metastasis was diagnosed more frequently in the non-MR group (5%) than in the MR group (2%). Preoperative MR screening of the brain can help early detection of brain metastases in the patients with lung adenocarcinoma prior to surgical resection and lead to increase postoperative survival in patients with operable lung adenocarcinoma.
机译:1999年5月以来,机构的指导方针三星医疗中心,韩国,首尔需要术前磁共振(先生)在所有患者肺癌筛查的大脑腺癌。自采用转移和生存率这条指导原则,我们回顾了病人的医疗记录1995年1月之间完成肺切除术2000年12月。和生存进行调查和比较在肺腺癌患者之间1999年5月接受完整切除之前,谁不接受筛查的大脑先生(non-MR吗后组,n = 160), 1999年5月,是谁干的接受筛查的大脑先生(MR集团n = 86)。先生组比non-MR组(p < 0.05),特别是前两年了。在网站除了大脑复发率两组之间的相似。生存在先生组(59%)高于non-MR组(45%,p < 0.05)。与I期癌症、脑转移诊断non-MR组的更频繁比奥组(5%)(2%)。大脑的检查有助于早期诊断脑转移的肺癌患者手术切除和前腺癌导致增加术后生存可操作的肺腺癌患者。

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