PIK3CA gene amplification in Japanese non-small cell lung cancer.

Kawano O; Sasaki H; Okuda KYukiue HYokoyama TYano MFujii Y

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PIK3CA gene amplification in Japanese non-small cell lung cancer.

机译：在日本非小PIK3CA基因扩增细胞肺癌。

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We have investigated 92 non-small cell lung cancer tissues and found 11 PIK3CA amplification. PIK3CA amplification incidence was significantly higher in male, smoker and squamous cell carcinoma patients. Among 11 patients with PIK3CA amplification, two patients harbored a PIK3CA mutation. There was significant difference in survival between the patients with PIK3CA normal copy number and the patients with PIK3CA amplification.

机译：我们调查了92个非小细胞肺癌组织和发现11 PIK3CA放大。放大发生率明显较高在男性,吸烟者和鳞状细胞癌病人。放大,两个病人存在PIK3CA突变。患者之间生存PIK3CA正常拷贝数和PIK3CA患者放大。

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《Lung cancer: Journal of the International Association for the Study of Lung Cancer》 |2007年第1期|159-160|共2页
作者
Kawano O; Sasaki H; Okuda KYukiue HYokoyama TYano MFujii Y;
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正文语种英语
中图分类肿瘤学;
关键词
PIK3CA gene; Non-Small-Cell Lung Carcinoma; Gene AmplificationSquamous Cell Carcinoma;

机译：PIK3CA基因;非小细胞肺癌;基因AmplificationSquamous细胞癌;

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机译：Adu; Aged;; Aged, 80 and over;; Antineoplastic Agents;; Carcinoma, Non-Small-Cell Lung;; Cisplatin;; Cohort Studies;; Deoxycytidine;; Female;; Humans;; Lung Neoplasms;; Male;; Middle Aged;; Mitomycin;; Neoadjuvant Therapy;; Neoplasm Staging;; Pneumonectomy;; Retrospective Studies;; Treatment Outcome;; Vinblastine;; *成年人;; 老年人;; 老年人, 80以上;; 抗肿瘤药;; 癌, 非小细胞肺;; 顺铂;; 队列研究;; 脱氧胞苷;; 肺肿瘤;; 肿瘤辅助疗法;; 肿瘤分期;; 肺切除术;; 回顾性研究;; 治疗结果;; 长春碱
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PIK3CA gene amplification in Japanese non-small cell lung cancer.

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