...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Lung cancer: Journal of the International Association for the Study of Lung Cancer >Reduction of organ motion in lung tumors with respiratory gating.
【24h】

Reduction of organ motion in lung tumors with respiratory gating.

机译：减少器官运动在肺肿瘤呼吸门控。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We evaluated the ability of a commercial respiratory gating system to assure the reproducibility of internal anatomy in respiration synchronized CT (RS-CT) scans. This passive system uses an infrared sensitive camera to track the motion of reflective markers mounted on the abdomen. Eighteen patients, nine with lung tumors and nine with liver tumors, were selected for evaluation of the Varian Real-Time Position Monitor respiratory gating system. Liver tumors were chosen as surrogate for lower lobe tumors. Each patient underwent at least two identical RS-CT scans, at end-inspiration (EI) or end-expiration (EE), to assess intra-fraction reproducibility. Twelve patients also underwent a free breathing scan and an opposed-respiration phase synchronized scan (EI if the two first were an EE and vice versa). On each CT, a physician contoured the liver, the kidneys, the spleen, and the diaphragms for the liver patients; and similarly, the lungs, the gross tumor volume (GTV), the trachea, the heart and the diaphragms for the lung patients. After registering the different CT images using bony anatomy, the changes of each structure between the respective data sets were quantified in terms of its volume, the displacement of its center of mass (COM), and an "index" coefficient of reproducibility. An analysis of the CT scans obtained at EI and EE phases yielded an average superior-inferior (SI) difference of the diaphragm position of 14.4 mm (range: 45.9-0.9). A similar analysis of CT scans acquired at the same breathing phase yielded 0.7 mm (range: 3.1-0, p=0.0001). Similar conclusions were derived in analysis of COM positions of the following structures: lungs, heart, lung's GTV, liver, spleen and kidneys. Evaluation of volume changes for lungs, liver, and spleen confirmed reproducibility of RS-CT while the "index" coefficient confirmed reproducibility of RS-CT of all organs. A commercial gating system using external markers for RS-CT significantly improves the positional reproducibility of thoracic and upper abdominal structures. This reproducible decrease in organ motion will allow a reduction of the margin of expansion facilitating increase in target dose beyond that allowed by conventional radiation treatments.
机译：我们评价一个商业的能力呼吸门控系统来保证内部解剖的再现性呼吸同步的CT扫描(RS-CT)。被动系统使用一个红外敏感的相机跟踪安装反光标记的运动在腹部。肿瘤与肝肿瘤和9,被选中瓦里安的评价实时位置监测呼吸门控系统。被选为代理下叶肿瘤。每个病人接受了至少两个相同的在end-inspiration RS-CT扫描,(EI)或end-expiration (EE),评估intra-fraction再现性。免费呼吸扫描和opposed-respiration相位同步扫描(EI如果一分之二EE,反之亦然)。波状外形的肝脏,肾脏,脾脏,对肝脏病人膜片;同样,肺部,总值肿瘤体积(制造),气管、心脏和隔膜肺癌患者。不同的CT图像,采用骨解剖每个结构之间各自的变化数据集被量化的体积,其质心的位移(COM)一个“索引”再现性系数。分析CT扫描获得的EI和情感表达阶段superior-inferior平均收益率(SI)14.4毫米的隔膜位置不同(范围:45.9 - -0.9)。获得在同一呼吸阶段产生了0.73.1毫米(范围:0,p = 0.0001)。派生的分析COM的位置吗以下结构:肺、心、肺的制造中心,肝脏、脾脏和肾脏。更改为肺、肝脏和脾脏的证实再现性的RS-CT而“指数”系数证实RS-CT的再现性所有的器官。外部标记RS-CT显著提高胸的位置再现性上腹部结构。减少器官运动将允许减少扩张促进利润的增长在目标剂量超出所允许传统的放射治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号