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Finger Agnosia and Cognitive Deficits in Patients with Alzheimer's Disease

机译:阿尔茨海默氏病患者的手指失认和认知缺陷

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The purpose of this study was to examine the presence of finger agnosia in patients with Alzheimer's disease (AD) and to determine if level of finger agnosia was related to cognitive impairment. Finger agnosia is a sensitive measure of cerebral impairment and is associated with neurofunctional areas implicated in AD. Using a standardized and norm-referenced approach, results indicated that patients with AD evidenced significantly decreased performance on tests of bilateral finger agnosia compared with healthy age-matched controls. Finger agnosia was predictive of cognitive dysfunction on four of seven domains, including: Crystallized Language, Fluid Processing, Associative Learning, and Processing Speed. Results suggest that measures of finger agnosia, a short and simple test, may be useful in the early detection of AD.
机译:这项研究的目的是检查阿尔茨海默氏病(AD)患者是否存在手指失明,并确定手指失明的水平是否与认知障碍有关。手指不可知是对脑损伤的一种敏感度量,它与AD相关的神经功能区域有关。使用标准化和规范参考的方法,结果表明,与健康的年龄匹配对照组相比,患有AD的患者在双侧手指无意识测试中的表现明显下降。手指不可知性可以预测七个领域中四个领域的认知功能障碍,包括:结晶语言,流体处理,联想学习和处理速度。结果表明,一种简单而又简单的测试方法是对手指的知觉度进行测量,这可能有助于早期发现AD。

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