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Precision Medicine Is Changing Cancer Care Forever

机译:精密医学是永远改变癌症治疗

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During the past 25 years as a medical oncologist, I have had the privilege of witnessing many exciting advancements in the battle against cancer. One of the most promising has been the emergence of precision medicine, an approach to patient care that enables physicians to select the most-effective treatments based on the generic makeup of a patient and the patient's underlying disease. Today we know about specific mutations that relate to how cancers start and spread. This information has led to targeted treatments. The more specific a treatment is to the cancer, the fewer the side effects to the patient and the more effective the treatment is likely to be. This is a dramatic shift from how cancer was primarily treated 10 or 15 years ago-and how it is still treated today if no molecularly targeted options exist. For example, chemotherapy is generally directed at rapidly dividing cells and DNA replication. Unfortunately, this can also be very detrimental to normal cells, which is why significant side effects are common with standard chemotherapy.
机译:在过去的25年里医疗肿瘤学家,我有幸见证许多激动人心的斗争中进步癌症。精密医学的出现,一个方法病人护理,使医生能够选择的治疗的基础上一般化妆品的病人和病人的潜在的疾病。突变与癌症如何开始传播。治疗方法。癌症,更少的副作用病人和更有效的治疗可能是。癌症主要是治疗10或15年并且它仍然是如何对待今天如果没有分子有针对性的选择存在。化疗通常是针对快速分裂细胞和DNA复制。不幸的是,这也可以是非常有害的正常细胞,这就是为什么重要的一面影响与标准化疗是常见的。

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