The cross-regulation between SOX15 and Wnt signaling pathway

Moradi Ali; Ghasemi Faezeh; Anvari KazemHassanian Seyed MahdiSimab Saeideh AhmadiEbrahimi SafiehHesari AmirrezaForghanifard Mohammad MahdiBoroushaki Mohammad TaherShahidSales SoodabehAvan Amir

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The cross-regulation between SOX15 and Wnt signaling pathway

机译：之间的cross-regulation SOX15和Wnt信号通路

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WNT/B-CATENIN signaling pathway is one of the key dysregulated pathways in different tumor types, which regulate the expression of several genes involved in cell proliferation, differentiation, and survival. This pathway is being modulated by sex-determining region Y-box (SOX) family genes. The functions of these genes are suggested as tumor suppressor or oncogene. SOX genes transcribe a group of transcription factors that play important roles in embryonic development and carcinogenesis. Among them, SOX15 is recently been identified as a novel tumor suppressor in pancreatic and esophagus cancers with a potential role in modulating Wnt/b-catenin signaling. This report summarizes the current knowledge about Wnt/b-catenin signaling pathway and its cross talk with SOX15 with particular emphasis on the value of SOX gene expression as prognostic or predictive biomarker in cancer.

机译：/ B-CATENIN WNT信号通路是关键之一在不同的肿瘤类型特异表达途径,调节多个基因的表达参与细胞增殖、分化、和生存。决定性别的地区Y-box (SOX)家族的基因。指出了这些基因的功能肿瘤抑制或致癌基因。转录的转录因子在胚胎发育和扮演重要的角色致癌作用。被确认为一种新的肿瘤抑制胰腺和食道癌症与潜力在调制/ b-catenin Wnt信号中的作用。报告总结了当前的知识/ b-catenin Wnt信号通路及其交叉跟SOX15特别强调SOX基因表达作为预后或价值预测生物标志物在癌症的。

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《Journal of Cellular Physiology》 |2017年第12期|3221-3225|共5页
作者
Moradi Ali; Ghasemi Faezeh; Anvari KazemHassanian Seyed MahdiSimab Saeideh AhmadiEbrahimi SafiehHesari AmirrezaForghanifard Mohammad MahdiBoroushaki Mohammad TaherShahidSales SoodabehAvan Amir;
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作者单位

Mashhad Univ Med Sci, Sch Med, Dept Med Biochem, Mashhad, Iran;

Mashhad Univ Med Sci, Fac Med, Dept Pharmacol, Mashhad, Iran;

Mashhad Univ Med Sci, Mol Med Grp, Sch Med, Dept Modern Sci & Technol, Mashhad, IranMashhad Univ Med Sci, Sch Med, Canc Res Ctr, Mashhad, IranIslamic Azad Univ, Damghan Branch, Dept Biol, Damghan, IranMashhad Univ Med Sci, Sch Med, Metab Syndrome Res Ctr, Mashhad, Iran;

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正文语种英语
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关键词
Tumor Suppressor Genes; Wnt Signaling Pathway PID; Transcription FactorsSOX15 geneWnt Signaling PathwayBiological MarkerscrosstalkCancerWNT;

机译：肿瘤抑制基因,Wnt信号通路PID;转录FactorsSOX15 geneWnt信号PathwayBiological MarkerscrosstalkCancerWNT;

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3. SIGNAL GTi: implementing task preemption and time intervals in the synchronous data flow language SIGNAL [C] . Rutten, E., Martinez, Real-Time Systems, 1995. Proceedings., Seventh Euromicro Workshop on . 1995

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4. Chinese International Students’ Narratives of Their Experiences in a Graduate Pathway Program: An Exploratory Study =探索式研究：中国留学生在美国研究生桥梁课程中的故事 [D] . Norstrand, Lu. 2020

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The cross-regulation between SOX15 and Wnt signaling pathway

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