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New insights in endometrial carcinogenesis

机译:子宫内膜癌形成的新见解

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摘要

Endometrial carcinoma is the most common cancer of the female genital tract in Europe and in the United States. Despite advances in defining the biology of endometrial carcinomas, there has been poor progress in determining markers that distinguish preinvasive endometrial proliferations. The aim of this review is to highlight the most recent studies regarding the molecular markers involved in endometrial adenocarcinoma pathogenesis and carcinogenesis. We focus on studies that describe markers with potential to progress from endometrial hyperplasia to invasive disease.
机译:子宫内膜癌是最常见的癌症在欧洲,女性生殖道美国。子宫内膜癌的生物学可怜的进步在确定标记区分蔓延前的子宫内膜那时。突出最近的研究有关分子标记参与子宫内膜腺癌发病机理和致癌作用。我们专注于研究描述标记从子宫内膜可能进步增生侵入性疾病。

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