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首页> 外文期刊>Current drug research reviews. >Use of Medications for the Treatment of Alcohol Dependence: A Retrospective Study Conducted in 2011-2012
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Use of Medications for the Treatment of Alcohol Dependence: A Retrospective Study Conducted in 2011-2012

机译:使用药物治疗酒精依赖:一项回顾性研究2011-2012

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Background: Pharmacotherapy for Alcohol Dependence (AD) is underutilized. Barriers preventing the use of AD medications include high prices, lack of access to prescribing physicians, and a limited number of available medications. Objective: The study evaluated the use of AD medications in a sample of Italian outpatients who received these medications free of charge, had access to physicians during office hours, and for whom substitution therapy [gamma-hydroxybutyrate (GHB)] was available. We also evaluated the rate of patients who received a combination of non-pharmacological and pharmacological treatments among participants who were still drinking. Methods:. SCID for AD and questionnaire were filled by to AD outpatients during a face-to-faee interview. Results & Discussion: 345 AD outpatients were interviewed: 58.8% were currently receiving at least one AD medication (GHB: 34.3%, disulfiram: 29.6%, acamprosate: 5.9%; naltrexone: 2.5%; more than one medication: 16.7%). Less than 30% of participants who were still drinking, received a combination of non-pharmacological and pharmacological treatments. Nonetheless, we found higher use of AD medications compared to previous studies conducted in other countries. This higher use of AD medications may be due to access to free medications, prescribing physicians' style, and a larger number of available medications. Conclusion: Our results confirm the underutilization of AD medications, as less than 60% of AD outpatients received medications, and less than 30% of those who were still drinking, received a combination of non-pharmacological and pharmacological treatments. These findings may be useful in improving our knowledge of the barriers that prevent the use of AD medications in clinical practice. Clinical Trial Registration: The Trial registry names were the following: (a) Comitato Etico ASL 1, Sassari, Italy; (b) Comitato Etico ASL 3, Nuoro, Italy; (c) Comitato Etico ASL 6, Sanluri, Italy; (d) Comitato Etico ASL 7, Carbonia, Italy. The registration identification numbers are the following: (a) ASL 1: Authorization no. 945 (February 28, 2011); (b) ASL 3: no. 1131 (October 27, 2011); (c) ASL 6: no. 35 (January 20, 2012); (d) ASL 7: no. 85 (April 21, 2011). The URL for the registry is the following: Azienda Tutela Salute Sardegna -Comitato Etico-L'azien-da-Organismi Aziendali-Comitato Etico (atssardegna.it).
机译:背景:药物治疗酒精依赖(广告)是没有得到充分的利用。使用广告药物包括高价格,所缺乏的获得处方医生,有限数量的可用药物治疗。目的:研究评估广告的使用药物在意大利门诊病人的样本免费接受这些药物,在办公时间访问医生,为谁替代疗法(γ(奸)]。评估病人的速度后备的结合参与者之间的药理治疗还喝酒。调查问卷是由广告门诊病人在face-to-faee面试。讨论:公元345年门诊病人接受了采访:58.8%是目前接收至少一个广告药物治疗(迷奸:34.3%,戒酒硫:29.6%,acamprosate: 5.9%;一个药物:16.7%)。参与者还喝酒,收到了后备和药物治疗。比以前更高的广告使用药物其他国家的研究。使用广告药物可能是由于访问权免费药物,处方医生的风格,和大量的药物。结论:我们的研究结果证实了未充分利用广告的药物,如不到60%的广告门诊病人接受了药物治疗不到30%的人仍然在喝,收到后备和药物治疗。有助于改善我们的知识障碍阻止广告药物的使用临床实践。试验注册名字是以下几点:(一)道德委员会ASL,萨萨里,意大利;道德委员会ASL 3诺,意大利;道德ASL 6、Sanluri、意大利;Carbonia手语7日,意大利。身份证号码如下:(一)美国手语1:没有授权。美国手语3:没有。不。(2011年4月21日)。出现了:公司健康保护撒丁岛- Etico-L’azien-da-Organismi道德Aziendali-Comitato (atssardegna . it)。

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