• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Cellular Physiology >Smart materials as scaffolds for tissue engineering.
【24h】

Smart materials as scaffolds for tissue engineering.

机译：智能材料作为组织支架工程。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this review, we focused our attention on the more important natural extracellular matrix (ECM) molecules (collagen and fibrin), employed as cellular scaffolds for tissue engineering and on a class of semi-synthetic materials made from the fusion of specific oligopeptide sequences, showing biological activities, with synthetic materials. In particular, these new intelligent specific for matrix metalloproteinases (MMPs), integrin binding domains, growth factors, anti-thrombin sequences, plasmin degradation sites, and morphogenetic proteins. The aim was to confer to these new "intelligent" semi-synthetic biomaterials, the advantages offered by both the synthetic materials (processability, mechanical strength) and by the natural materials (specific cell recognition, cellular invasion, and the ability to supply differentiation/proliferation signals). Due to their characteristics, these semi-synthetic biomaterials represent a new and versatile class of biomimetic hybrid materials that hold clinical promise in serving as implants to promote wound healing and tissue regeneration.
机译：在本文中,我们集中我们的注意力集中在更重要的是天然细胞外基质(ECM)分子(胶原蛋白和纤维蛋白),使用为组织工程细胞支架一个类的半合成材料制成的特定的寡肽序列的融合,显示生物活性,合成材料。具体对基质金属蛋白酶(MMPs),整合素结合域,生长因子,anti-thrombin序列,血纤维蛋白溶酶降解网站,形态形成的蛋白质。赋予这些新的“智能”半合成品生物材料,所提供的优势合成材料(加工性、机械由天然材料强度)和(具体细胞识别、细胞入侵和供应/增殖分化能力信号)。半合成生物材料代表了一个新的多才多艺的一类仿生混合材料持有临床承诺作为植入物促进伤口愈合和组织再生。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号