cDNA array technology in melanoma: An overview.

Baldi A; Santini D; Uca Ade LPaggi MG

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cDNA array technology in melanoma: An overview.

机译：互补脱氧核糖核酸阵列技术在黑色素瘤:概述。

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摘要

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma. J. Cell. Physiol. 196: 219-223, 2003.

机译：基因畸变,主要导致的变化在基因表达,在癌症的关键事件发病和进展。技术允许筛查和数组有效的测量成千上万的表情同时在一个广泛的基因实验和临床模型。目前规模的方法被用于获得全球人类癌症基因表达的观点识别可能的遗传标记重要的诊断、预后和治疗。本文讨论了最近的一些发现通过cDNA数组调查获得的人类黑色素瘤。219-223, 2003.

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来源
《Journal of Cellular Physiology》 |2003年第2期|219-223|共5页
作者
Baldi A; Santini D; Uca Ade LPaggi MG;
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作者单位

Regina Elena Cancer Institute, CRS, Via delle Messi d'Oro, Rome, Italy.;

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原文格式 PDF
正文语种英语
中图分类细胞生物学;
关键词
Melanoma; DNA; cDNA ArrayComplementary;

机译：黑色素瘤;DNA;cDNA ArrayComplementary;

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cDNA array technology in melanoma: An overview.

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