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首页> 外文期刊>Clinical obesity. >Development of endometrioid adenocarcinoma despite Levonorgestrel-releasing intrauterine system: a case report with discussion and review of the RCOG/BSGE Guideline on the Management of Endometrial Hyperplasia
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Development of endometrioid adenocarcinoma despite Levonorgestrel-releasing intrauterine system: a case report with discussion and review of the RCOG/BSGE Guideline on the Management of Endometrial Hyperplasia

机译：endometrioid腺癌尽管发展Levonorgestrel-releasing宫内系统:a病例报告与讨论和审查之内/ BSGE的管理方针子宫内膜增生

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摘要

Obesity is a significant risk factor for the development of endometrial hyperplasia and cancer. More conservative prevention and management strategies are attractive due to the increased surgical risk and complication rates associated with obesity. The Levonorgestrel-releasing intrauterine system (LNG-IUS, Mirena) has been shown to reduce the risk of developing endometrial cancer. The recent joint Green Top Guideline on the Management of Endometrial Hyperplasia published by the Royal College of Obstetricians and Gynaecologists (RCOG) with the British Society for Gynaecological Endoscopy (BSGE) recommends the LNG-IUS for the medical management of endometrial hyperplasia without atypia. This case study reports on the development of endometrioid adenocarcinoma despite the presence of an LNG-IUS following a negative hysteroscopy in a 56-year-old woman with morbid obesity. This report highlights the need for patients and clinicians to remain vigilant to the early warning signs of developing endometrial cancer, especially in those at an increased risk secondary to obesity.
机译：肥胖是一个重要的危险因素子宫内膜增生和发展癌症。由于管理策略是有吸引力增加手术的风险和并发症发生率与肥胖有关。Levonorgestrel-releasing子宫内的系统(宫内节育器曼月乐LNG-IUS)已被证明会降低患子宫内膜癌的风险。联合绿色管理的最高指导原则子宫内膜增生皇家出版妇产科学院之内的英国社会妇科内镜(BSGE)建议LNG-IUS医疗管理的子宫内膜没有异型性增生。报告endometrioid的发展腺癌尽管LNG-IUS的存在负后子宫镜检查56岁的病态肥胖的女人。报告强调了患者和需要临床医生早期保持警惕患子宫内膜癌的征兆,特别是在风险增加继发性肥胖。

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