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首页> 外文期刊>Journal of diabetes. >Reference intervals for serum 1,5‐anhydroglucitol of a population with normal glucose tolerance in Jiangsu Province
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Reference intervals for serum 1,5‐anhydroglucitol of a population with normal glucose tolerance in Jiangsu Province

机译：参考区间血清1 5 anhydroglucitol与正常糖耐量人群江苏省

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Abstract Background Serum 1,5‐anhydroglucitol (1,5‐AG) is a new glycemic marker which can reflect glucose fluctuation over 3 to 7?days and is now increasingly used to monitor glucose control and to screen for diabetes. However, 1,5‐AG has not been widely used in China due to lack of epidemiological support. Our study aims to establish the reference intervals for a population with normal glucose tolerance in Jiangsu Province and to explore the determinants of these intervals. Method The study enrolled 646 healthy adults aged 20 to 70?years in Jiangsu Province in 2018 after oral glucose tolerance test. 1,5‐AG, fasting and 2‐hour glucose, UA, liver enzyme, serum lipid, creatinine, and glycosylated hemoglobin were measured. We calculated reference intervals using the parametric method and examined the relationship between 1,5‐AG and influence factors. Results The average age of the participants was 50.5?±?9.0?years, and 69.5% of them were females. The reference intervals were 15.8 to 52.6?μg/mL for males and 14.3 to 48.0?μg/mL for females. Among females, the reference intervals were 13.9 to 45.3 and 14.6 to 49.6?μg/mL for menopausal and postmenopausal females, respectively. Males showed higher 1,5‐AG concentrations than females, and postmenopausal females had higher 1,5‐AG than menopausal females. There was a positive correlation between uric acid and 1,5‐AG in both genders. Positive correlation between 1,5‐AG and age was only observed in females. Conclusion We established reference intervals for 1,5‐AG in Jiangsu Province, and the level of 1,5‐AG is affected by sex, uric acid, and age.
机译：抽象背景血清1 5 anhydroglucitol(1、5公/ AG)是一种新的血糖可以标志在3 - 7反映血糖波动?现在越来越多地用于监测血糖糖尿病控制和筛选。1、5列车AG)由于在中国没有被广泛使用缺乏流行病学支持。建立的参考区间与正常糖耐量人群江苏省和探索的决定因素这些间隔。20至70岁的健康成年人?省2018年口服葡萄糖耐量测试。肝酶、血清脂质、肌酐和糖化血红蛋白测定。计算参考使用参数方法和检查的关系1、5 AG)和影响因素。参与者的平均年龄9.0±50.5 ? ?参考间隔15.8到52.6吗?男性和14.3到48.0吗?在女性中,参考间隔是13.945.3和14.6到49.6吗?绝经后女性,分别。显示更高的1、5高AG浓度比女性和绝经后的女性有更高的1、5 AG)比更年期女性。尿酸的相关性和1 5 AG)在两种性别。年龄只是观察到的女性。建立参考间隔1 5列车AG)江苏省和水平的1 5列车AG)受性别、尿酸、和年龄。

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