Renoprotective effects of berberine and its potential effect on the expression of -arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats

Tang Li-Qin; Ni Wei-Jian; Cai MingDing Hai-HuaLiu ShengZhang Shan-Tang

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Renoprotective effects of berberine and its potential effect on the expression of -arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats

机译：Renoprotective小檗碱及其影响潜在影响-arrestins的表达和细胞间粘附molecule-1血管细胞粘附molecule-1streptozocin-diabetic肾病大鼠

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BackgroundBerberine has been shown to exert protective effects against diabetic nephropathy (DN), but the mechanisms involved have not been fully characterized. The aim of the present study was to explore the effects of berberine on the expression of -arrestins, intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in DN rat kidneys and investigate the underlying molecular mechanisms.

机译：BackgroundBerberine已经产生保护作用对糖尿病肾病(DN),但没有涉及的机制充分的特点。探讨小檗碱的影响在吗-arrestins表达,在细胞间的细胞附着力molecule-1 (ICAM-1)和血管细胞附着力molecule-1 (VCAM-1)在DN大鼠肾脏并研究了潜在的分子机制。

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《Journal of diabetes》 |2016年第5期|693-700|共8页
作者
Tang Li-Qin; Ni Wei-Jian; Cai MingDing Hai-HuaLiu ShengZhang Shan-Tang;
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作者单位

Anhui Med Univ, Affiliated Anhui Prov Hosp, Hefei, Anhui, Peoples R China;

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正文语种英语
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Diabetic Nephropathies; Arrestins; Kidney DiseasesCell Adhesion MoleculesBerberineVascular Cell Adhesion Molecule-1Intercellular Adhesion Molecule-1;

机译：糖尿病肾病;Arrestins;肾脏DiseasesCell粘附MoleculesBerberineVascular细胞粘附Molecule-1Intercellular附着力Molecule-1;

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Renoprotective effects of berberine and its potential effect on the expression of -arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats

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