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首页> 外文期刊>Pain practice: the official journal of World Institute of Pain >Preliminary observations of a novel topical oil with analgesic properties for treatment of acute and chronic pain syndromes.
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Preliminary observations of a novel topical oil with analgesic properties for treatment of acute and chronic pain syndromes.

机译：一本小说的初步观察局部油与镇痛治疗急性的属性和慢性疼痛综合症。

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Objective: Essential oxygen oil (OxyRub from CreoMed Inc., Naples, FL, U.S.A.) is a novel topical analgesic currently commercially available in Europe and now available in the U.S.A. It represents an important alternative to other treatments (nonsteroidal anti-inflammatory drugs, acetaminophen, menthol, camphor) for managing mild to moderate acute and chronic pain. Several clinical trials of this oil will be reviewed. Results: One large (n = 455) open-label trial found essential oxygen oil to be a safe and effective analgesic for a broad range of patients with acute and chronic pain. In that study, 80% of patients reported that their pain decreased by more than 75%. A double-blind placebo-controlled study (n = 50) found significant pain reduction for tendonitis in patients using essential oxygen oil. Another trial of essential oxygen oil vs. placebo (n = 50) with various pain diagnoses found that 98% of patients with various pain diagnoses reported "very good" pain relief in the oil group compared to 48% in the placebo group. Furthermore, a randomized controlled trial in 10 women to measure oxygen microcirculatory effect in the skin showed an increased microcirculatory effect with improved oxygenation (increased partial pressure of oxygen in the skin) after application of essential oxygen oil. In all studies, the oil was well tolerated. None of these studies has been previously published. Conclusions: Based on studies completed, essential oxygen oil has shown itself to be safe, has demonstrated positive analgesic effects for the treatment of acute and chronic pain, and has improved oxygen content in the skin as well as other dermatological parameters.
机译：摘要目的:石油(OxyRub至关重要的氧气CreoMed Inc .)、那不勒斯、FL,美国)是一部小说局部镇痛目前商业在欧洲,现在可用的美国是一个重要的选择其他治疗(非甾体类抗炎药物、对乙酰氨基酚、薄荷脑、樟脑)管理轻度至中度急性和慢性疼痛。几个临床试验,这种油回顾。试验发现必要的氧气石油安全对广泛的病人有效的止痛剂急性和慢性疼痛。的病人报告说,他们的痛苦减少了超过75%。(n = 50)的研究发现显著的减少疼痛肌腱炎的病人使用必要的氧气石油。安慰剂组(n = 50)各种疼痛的诊断发现,98%的患者各种痛苦诊断报告“非常好”缓解疼痛石油集团相比安慰剂组的48%。此外,在10个随机对照试验女性测量氧气microcirculatory效果在皮肤上显示microcirculatory增加效果与改进的氧化(增加氧气分压后的皮肤)石油的应用至关重要的氧气。研究中,石油是耐受性良好。这些研究已经以前公布。结论:基于研究完成后,至关重要的氧气油显示本身是安全的,有了积极的镇痛效果急性和慢性疼痛的治疗,改善皮肤氧含量以及其他皮肤参数。

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