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首页> 外文期刊>Ophthalmic surgery, lasers & imaging: the official journal of the International Society for Imaging in the Eye >Macular thickness measurements in normal eyes using spectral domain optical coherence tomography.
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Macular thickness measurements in normal eyes using spectral domain optical coherence tomography.

机译：黄斑厚度测量在正常的眼睛使用光谱域光学相干断层扫描。

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摘要

BACKGROUND AND OBJECTIVE: Knowledge of the macular thickness in a normal population is important for the evaluation of pathological macular change. The purpose of this study was to define and measure macular thickness in normal eyes using spectral domain optical coherence tomography (OCT). PATIENTS AND METHODS: Fifty eyes from 50 normal subjects (29 men and 21 women, aged 22 to 68 years) were scanned with a prototype Cirrus HD-OCT system (5 microm axial resolution) (Carl Zeiss Meditec, Inc.). The proprietary Cirrus segmentation algorithm was used to produce retinal thickness maps, which were then averaged over 9 regions defined by a circular target centered at the true fovea location. The macular thickness of 13 subjects scanned with both HD-OCT and StratusOCT were compared. RESULTS: After centering the fovea, the mean and standard deviation values for retinal thickness measurements were calculated point wise and averaged on standard regions. For patients scanned with both systems, the thickness measurements from HD-OCT were approximately 50 microm larger than those from StratusOCT. The difference between the two measurements decreased somewhat with eccentricity. CONCLUSION: Using HD-OCT, it is possible to acquire retinal data sets containing an unprecedented number of data points. Furthermore, it is possible to use OCT fundus images to evaluate the scan quality and to center the measurement at the fovea. These advantages, together with good automated segmentation, can produce more accurate retinal thickness measurements. Incorporation of the photoreceptor layer in the measurements is anatomically meaningful and may be significant in evaluating various retinal pathologies and visual acuity outcomes.
机译：背景和目的:黄斑的知识厚度在正常人口是很重要的病态的评价黄斑变化。本研究的目的是定义和测量眼睛黄斑厚度在正常使用光谱域光学相干断层扫描(10月)。正常人(29男21岁女,22岁68年)进行扫描原型卷HD-OCT系统(5 microm轴向分辨率)(卡尔蔡司Meditec制造Inc .)。分割算法被用于生产视网膜厚度地图,然后取平均值超过9区域定义为一个圆形的目标集中在真正的中央位置。厚度扫描与HD-OCT 13课程和StratusOCT相比。中心凹,平均值和标准视网膜厚度的偏差值明智的和测量计算点平均标准的地区。与两个系统扫描,厚度测量从HD-OCT大约50从StratusOCT microm大比。区别这两个测量下降有些古怪。视网膜HD-OCT,可以获得数据包含空前数量的数据集点。眼底图像来评估质量和扫描中心凹的测量。优势,加上良好的自动化分割,可以产生更精确的视网膜厚度测量。在测量感光层在解剖学上有意义的和可能是重要的评估各种视网膜疾病和视觉敏度的结果。

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