Automating the application of smart materials for protein crystallization

Khurshid Sahir; Govada Lata; El-Sharif Hazim F.Reddy Subrayal M.Chayen Naomi E.

首页> 外文期刊>Acta crystallographica. Section D, Biological crystallography. >Automating the application of smart materials for protein crystallization

【24h】

Automating the application of smart materials for protein crystallization

机译：自动化智能材料的应用蛋白质结晶

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The fabrication and validation of the first semi-liquid nonprotein nucleating agent to be administered automatically to crystallization trials is reported. This research builds upon prior demonstration of the suitability of molecularly imprinted polymers (MIPs; known as 'smart materials') for inducing protein crystal growth. Modified MIPs of altered texture suitable for high-throughput trials are demonstrated to improve crystal quality and to increase the probability of success when screening for suitable crystallization conditions. The application of these materials is simple, time-efficient and will provide a potent tool for structural biologists embarking on crystallization trials.

机译：第一的制造和验证半流质的非蛋白的成核剂管理自动结晶试验报告。之前展示的适用性分子印迹聚合物(MIPs;“智能材料”)诱导蛋白质晶体增长。高通量试验证明提高晶体质量和增加筛查时成功的可能性合适的结晶条件。应用这些材料很简单,省时间,将提供一个强有力的工具结构生物学家开始结晶试验。

著录项

来源
《Acta crystallographica. Section D, Biological crystallography.》 |2015年第3期|534-540|共7页
作者
Khurshid Sahir; Govada Lata; El-Sharif Hazim F.Reddy Subrayal M.Chayen Naomi E.;
展开▼
作者单位

Univ London Imperial Coll Sci Technol & Med, Fac Med, Dept Surg & Canc, Computat & Syst Med, London;

Univ Surrey, Fac Engn & Phys Sci, Dept Chem, Guildford GU2 7XH, Surrey, England;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类
关键词
Molecularly imprinted polymers; protein crystal growth; million instructions per secondSmart materialsAutomationCrystallization;

机译：分子印迹聚合物;蛋白质晶体经济增长;每secondSmart百万指令materialsAutomationCrystallization;

相似文献

外文文献
中文文献
专利

1. Technical crystallization for application in pharmaceutical material engineering:Review article [J] . Abdul Khaliq El-Zhry El-Yafi, Hind El-Zein 亚洲药物制剂科学(英文) . 2015,第004期
2. Erratum: A wideband, frequency up-converting bounded vibration energy harvester for a low frequency environment (Smart Materials and Structures (2013) 22 (025018)) [J] . Ashraf K., Md Khir M.H., Dennis J.O., Smart Materials & Structures . 2013,第4期

机译：勘误表：一种用于低频环境的宽带，频率上变频有界振动能量采集器（Smart Materials and Structures（2013）22（025018））
3. Erratum: An electromechanically coupled micro-sphere framework - Application to the finite element analysis of electrostrictive polymers (Smart Materials and Structures (2012) 21 (094008)) [J] . Thylander S., Menzel A., Ristinmaa M. Smart Materials & Structures . 2013,第3期

机译：勘误：机电耦合的微球框架-在电致伸缩聚合物的有限元分析中的应用（Smart Materials and Structures（2012）21（094008））
4. Erratum: Designing maximum power output into piezoelectric energy harvesters (Smart Materials and Structures (2012) 21 (085008)) [J] . Shafer M.W., Bryant M., Garcia E. Smart Materials & Structures . 2012,第10期

机译：勘误表：设计输出到压电能量收集器的最大功率（Smart Materials and Structures（2012）21（085008））
5. Proper Selection of the Materials of Construction for Cooling Towers in Commercial HVAC and Industrial Applications [C] . FRANK MORRISON Cooling Technology Institute Annual conference . 2007

机译：Proper Selection of the Materials of Construction for Cooling Towers in Commercial HVAC and Industrial Applications
6. Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2 [D] . Yu, Qinhong. 2019

机译：Structure Determination and Mechanistic Insights of: I.Cyanobacteriochrome NpR6012g4 Light Sensor Protein in Phototaxis II.Retinal Degeneration 3 (RD3) Protein in Vision III.Ryanodine Receptor 2 (RyR2) Regulation by Calmodulin (CaM) in Cardiac Function =结构测定和机理洞悉：I.趋光性中的蓝细菌色素NpR6012g4光敏蛋白 II.视觉作用中的视网膜退化蛋白3 III.心脏功能中的钙调蛋白调控兰诺定受体2
7. Complex proteinopathy with accumulations of prion protein hyperphosphorylated tau α-synuclein and ubiquitin in experimental bovine spongiform encephalopathy of monkeys [O] . Pedro Piccardo, Juraj Cervenak, Ming Bu, -1

机译：猴子protein牛海绵状脑病中protein蛋白高磷酸化tauα-突触核蛋白和泛素积累的复杂蛋白病
8. Crystallization and preliminary X-ray diffraction analysis of the N-terminal domain of human coronavirus OC43 nucleocapsid protein [O] . Chen I.J., Chou C.C., Liu C.L., 2014

机译：Crystallization and preliminary X-ray diffraction analysis of the N-terminal domain of human coronavirus OC43 nucleocapsid protein
9. Inledande Mekaniska Studier av Riktade Wolfrma-Rheniumlegeringar (Scaling Laws and Material Dynamic Material Behavior). [R] . Skoglund, P., Savage, S. J. 2000

机译：Inledande mekaniska studier av Riktade Wolfrma-Rheniumlegeringar（scaling Laws and material Dynamic material Behavior）。

Automating the application of smart materials for protein crystallization

摘要

著录项

相似文献

相关主题

期刊订阅