...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Archives of Neurology >Essential tremor associated with pathologic changes in the cerebellum.
【24h】

Essential tremor associated with pathologic changes in the cerebellum.

机译：特发性震颤与病理相关小脑的变化。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Although essential tremor (ET) is one of the most common neurologic disorders, there have been few postmortem studies. We recently reported postmortem changes (torpedoes and Bergmann gliosis) in the cerebellar cortex in a few ET cases. OBJECTIVE: To describe more extensive postmortem changes in the cerebellum in another ET case. DESIGN: Case report. RESULTS: A 90-year-old woman had a 30-year history of ET. At postmortem examination, there was segmental loss of Purkinje cells, presence of torpedoes, and Bergmann gliosis in the cerebellar cortex. Moreover, there were extensive changes in the dentate nucleus, in the form of neuronal loss, neuronal atrophy, microglial clusters, and reduction in the number of efferent fibers (ie, pallor of the hilum). CONCLUSIONS: The brain in the current case exhibited more marked cerebellar pathologic features than noted in previously reported ET cases and thereby extends the described cerebellar findings in this common, yet pathologically poorly characterized, neurologic disorder.
机译：背景:虽然特发性震颤(ET)就是其中之一最常见的神经系统疾病,一些后期研究。后期的变化(鱼雷和报道伯格曼在小脑皮质神经胶质过多症)少等情况。广泛的后期改变小脑另一个等情况。90岁的女人有30年的历史等。尸检,节段性损失鱼雷的浦肯野细胞的存在,伯格曼在小脑皮质神经胶质过多症。此外,有广泛的变化齿状核神经元损失的形式,神经萎缩,小胶质集群减少数量的传出纤维(即苍白的门)。当前情况下表现出更多的小脑比之前在病理特征报道等情况,从而扩展了描述小脑的发现在这个共同的病理上差的特点,神经障碍。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号