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首页> 外文期刊>Acta crystallographica.Section D. Biological crystallography >A unified convention for biological assemblies with helical symmetry.
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A unified convention for biological assemblies with helical symmetry.

机译:一个统一的生物组件公约与螺旋对称。

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摘要

Assemblies with helical symmetry can be conveniently formulated in many distinct ways. Here, a new convention is presented which unifies the two most commonly used helical systems for generating helical assemblies from asymmetric units determined by X-ray fibre diffraction and EM imaging. A helical assembly is viewed as being composed of identical repetitive units in a one- or two-dimensional lattice, named 1-D and 2-D helical systems, respectively. The unification suggests that a new helical description with only four parameters [n(1), n(2), twist, rise], which is called the augmented 1-D helical system, can generate the complete set of helical arrangements, including coverage of helical discontinuities (seams). A unified four-parameter characterization implies similar parameters for similar assemblies, can eliminate errors in reproducing structures of helical assemblies and facilitates the generation of polymorphic ensembles from helical atomic models or EM density maps. Further, guidelines are provided for such a unique description that reflects the structural signature of an assembly, as well as rules for manipulating the helical symmetry presentation.
机译:程序集与螺旋对称方便地制定在很多不同的方式。在这里,一个新的公约提出了统一两种最常用的螺旋系统从非对称生成螺旋总成单位由x射线纤维衍射和决定电磁成像。在一个相同的重复单位构成的或二维晶格,命名为一维,二维螺旋系统,分别。表明一个新的螺旋只有描述四个参数(n(1),(2)、扭曲、上升),被称为一维螺旋增强系统,可以吗生成完整的螺旋安排,包括螺旋的报道不连续(缝)。描述意味着类似的参数类似的组件,可以消除错误螺旋结构组件和繁殖促进多态的生成从螺旋原子模型或EM集合体密度地图。对于这样一个独特的描述,反映了结构组装的签名,以及操纵规则螺旋对称演示。

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