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首页> 外文期刊>Acta crystallographica.Section D. Biological crystallography >Investigations of surrogate cellular membranes using neutron reflectometry.
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Investigations of surrogate cellular membranes using neutron reflectometry.

机译：调查代理细胞膜使用中子反射计。

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摘要

The nonperturbative nature of neutron reflectometry (NR) coupled with its isotopic sensitivity has made it an ideal candidate for the study of model biological membranes at the solid-liquid interface. In this article, methods are presented for the creation and characterization of supported model membranes which can mimic many of the critical attributes of cell membranes. It is demonstrated that NR can characterize the structure, composition and organization of model membranes deposited on solid, nanoporous and polymer supports. Additionally, in situ NR measurements of the interactions between model membranes and external stimuli are presented. Finally, an investigation of the adherence region of live mouse fibroblast cells is described.
机译：中子的nonperturbative性质反射计(NR)加上它的同位素敏感性使得它成为了一个理想的候选人生物膜的研究模型固液界面。提出了创建和吗膜特性支持的模型可以模仿许多关键属性细胞膜。描述的结构、组成和膜沉积在组织模型固体,纳米多孔聚合物支持。此外,原位NR的测量膜和外部之间的交互模型刺激。坚持区域的活鼠成纤维细胞细胞被描述。

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