In the title compound [systematic name: 7-(2-deoxy-beta-D-erythro -pentofuranosyl) -2-fluoro-7H-pyrrolo[2,3 -d]pyrimidin-2-amine], C11H13FN4O3, the conformation of the N-glycosylic bond is between and and high-anti [x = -110.2 (3)deg]. The 2'-deoxyribofuranosyl unit adopts the iV-type sugar pucker (4T~3), with P = 40.3deg and Tm = 39.2deg. The orientation of the exocyclic C4'-C5' bond is - ap (trans), with a torsion angle gamma = -168.39 (18)deg. The nucleobases are arranged head-to-head. The crystal structure is stabilized by four intermolecular hydrogen bonds of types N-H...N, N-H...O and O-H...O.
展开▼
