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Osteopetrosis in a young adult dog causing multiple cranial nerve deficits

机译:年轻的成年狗导致骨硬化病多发性颅神经赤字

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a two-year-old Cocker spaniel was presented for investigation of lethargy and cranial nerve deficits. neurological examination revealed multiple cranial nerves deficits and haematology and serum biochemistry revealed mild anaemia. Mn of the brain revealed caudoventral cerebellar herniation and cervical syringohydromyelia, while both MRI and CT revealed hyperostosis of the calvarium and narrowing of the calvarial foramina. Radiographs demonstrated marked osteosclerosis of the skull, vertebrae, sternebrae, ribs and long bones of the limbs. Further biochemistry revealed total calcium, ionised calcium and vitamin D levels to be unremarkable. This led to a diagnosis of osteopetrosis. Osteopetrosis is an extremely rare condition in dogs, with only sporadic cases being reported previously in the literature.
机译:提出了一个两岁的小猎犬调查的嗜睡和颅神经赤字。多发性颅神经赤字和血液学和血清生化显示轻度贫血。的大脑显示caudoventral小脑颈椎间盘突出syringohydromyelia,MRI和CT显示骨肥大的颅盖和缩小的颅顶的小孔。骨硬化的头骨,脊椎,sternebrae,肋骨和长骨头的四肢。进一步的生物化学显示总钙、离子钙和维生素D的水平不起眼的。骨硬化病。条件的狗,只有零星病例以前的文献报道。

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