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首页> 外文期刊>Veterinary Record Case Reports >Thoracolumbar myelopathy with diffuse vertebral involvement in a dog secondary to aleukaemic lymphocytic leukaemia
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Thoracolumbar myelopathy with diffuse vertebral involvement in a dog secondary to aleukaemic lymphocytic leukaemia

机译：胸腰椎脊髓病椎扩散参与狗二级aleukaemic淋巴细胞性白血病

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摘要

Incidence rate of lymphocytic leukaemia is unknown in canine patients; neurological manifestations and imaging findings are rarely reported. In human medicine, acute lymphocytic leukaemia is known to have a high rate of meningeal metastasis promptingthe use of intrathecal chemotherapy for newly diagnosed cases regardless of neurological signs. This report documents the clinical presentation and diagnostic findings in a dog presenting with paraparesis and pain, ultimately diagnosed with aleukaemic lymphocytic leukaemia. MRI findings with diffuse vertebral involvement secondary to lymphocytic leukaemia have not been documented in the veterinary literature. This report adds to the clinical presentations of leukaemia in canines and highlights a neurological sequela of the disease. Further investigation into neurological involvement of leukaemia is needed in veterinary medicine and necropsy, with meningeal histopathology, is recommended for all cases of acute lymphocytic leukaemia in canines to assessthe metastatic rate and direct further research.
机译：淋巴细胞性白血病的发病率是未知的在犬的病人;和成像结果很少报道。人类医学,急性淋巴细胞性白血病是脑膜转移率高promptingthe鞘内化疗的使用新诊断病例神经无关的迹象。表示和诊断发现一只狗出现下肢轻瘫和痛苦,最终诊断出患有aleukaemic淋巴细胞白血病。核磁共振的发现与扩散椎参与二级淋巴细胞白血病没有记录在兽医文学。报告补充说的临床表现白血病在狗和凸显了神经系统疾病的后遗症。调查神经的参与白血病是兽医和需要尸体剖检,与脑膜组织病理学建议所有例急性淋巴细胞白血病在狗定位转移率和直接的进一步研究。

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