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首页> 外文期刊>Archives of Internal Medicine >Magnesium, calcium, potassium, and sodium intakes and risk of stroke in male smokers.
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Magnesium, calcium, potassium, and sodium intakes and risk of stroke in male smokers.

机译：镁,钙,钾,钠摄入量,在男性吸烟者患中风的风险。

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BACKGROUND: A high intake of magnesium, calcium, and potassium and a low intake of sodium have been hypothesized to reduce the risk of stroke. However, prospective data relating intake of these minerals to risk of stroke are inconsistent. METHODS: We examined the relationship of dietary magnesium, calcium, potassium, and sodium intake with risk of stroke in a cohort of 26 556 Finnish male smokers, aged 50 to 69 years, who were free from stroke at baseline. Dietary intake was assessed at baseline using a detailed and validated food frequency questionnaire. During a mean follow-up of 13.6 years (1985-2004), 2702 cerebral infarctions, 383 intracerebral hemorrhages, and 196 subarachnoid hemorrhages were identified in the national registries. RESULTS: After adjustment for age and cardiovascular risk factors, a high magnesium intake was associated with a statistically significant lower risk of cerebral infarction but not with intracerebral or subarachnoid hemorrhages. The multivariate relative risk of cerebral infarction was 0.85 (95% confidence interval, 0.76-0.97; P for trend = .004) for men in the highest quintile of magnesium intake compared with those in the lowest quintile. The inverse association between magnesium intake and cerebral infarction was stronger in men younger than 60 years (relative risk, 0.76; 95% confidence interval, 0.64-0.89; P for interaction = .02). Calcium, potassium, and sodium intake was not significantly associated with risk of any subtype of stroke (P for trend > .05). CONCLUSION: These findings in male smokers suggest that a high magnesium intake may play a role in the primary prevention of cerebral infarction.
机译：背景:高摄入量的镁、钙、和钾低钠的摄入被假设能降低中风的危险。然而,潜在的摄入相关的数据这些矿物质中风的风险不一致的。饮食关系镁、钙、钾,钠摄入量与中风的风险在一群26 556芬兰男性吸烟者年龄50到69年,免费从中风基线。使用一个详细的和食物频率进行验证问卷调查。2702年(1985 - 2004),脑梗死,383颅内出血,196蛛网膜下腔出血被确定在国家注册中心。心血管危险因素,高镁摄入量与统计学关联显著降低脑梗塞的风险不与颅内蛛网膜下腔出血。脑梗死是0.85(95%的信心区间,0.76 - -0.97;排位最高的镁的摄入量相比之下,排位最低的。逆镁摄入量和之间的联系脑梗死是更强的年轻男性超过60年(相对风险,0.76;置信区间,0.64 - -0.89;= .02点)。不显著相关的任何风险子类型中风的趋势(P > . 05)。结论:这些发现男性吸烟者表明,镁摄入会很高在大脑的初级预防中的作用梗塞。

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