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首页> 外文期刊>Archives of Internal Medicine >Colonoscopy screening in African Americans and Whites with affected first-degree relatives.
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Colonoscopy screening in African Americans and Whites with affected first-degree relatives.

机译：结肠镜筛查的非洲裔美国人白人与一级亲属的影响。

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BACKGROUND: Family history is a risk factor for colon cancer, and guidelines recommend initiating screening at age 40 years in individuals with affected relatives. Racial differences in colon cancer mortality could be related to variations in screening of increased-risk individuals. METHODS: Baseline data from 41 830 participants in the Southern Community Cohort Study were analyzed to determine the proportion of colonoscopy procedures in individuals with strong family histories of colon cancer, and whether differences existed based on race. RESULTS: In participants with multiple affected first-degree relatives (FDRs) or relatives diagnosed before age 50 years, 27.3% (95% confidence interval [CI], 23.5%-31.1%) of African Americans reported having a colonoscopy within the past 5 years compared with 43.1% (95% CI, 37.0%-49.2%) of white participants (P<.001). African Americans in this group had an odds ratio of 0.51 (95% CI, 0.38-0.68) of having undergone recommended screening procedures compared with white participants after adjusting for age, sex, educational status, annual income, insurance status, total number of affected and unaffected FDRs, and time since last medical visit. African Americans with multiple affected FDRs or relatives diagnosed before age 50 years and who had ever undergone endoscopy were less likely to report a personal history of colon polyps (odds ratio, 0.29; 95% CI, 0.20-0.42) when compared with whites with similar family histories. CONCLUSIONS: African Americans who have FDRs with colon cancer are less likely to undergo colonoscopy screening compared with whites who have affected relatives. Increased efforts need to be directed at identifying and managing underserved populations at increased risk for colon cancer based on their family histories.
机译：背景:家庭的历史是一个风险因素结肠癌,指南建议启动在患者筛查40岁年亲戚的影响。癌症死亡率可能与变化筛查的风险增加的个人。方法:从41 830参与者基线数据在南部社区队列研究分析确定的比例结肠镜检查过程和强烈的个人结肠癌家族史,是否基于种族差异。参与者与多个一级的影响亲戚(罗斯福)或亲属诊断50岁,27.3%(95%置信区间(CI), 23.5% - -31.1%)的非裔美国人报道在过去5年内在结肠镜检查比例为43.1%(95%可信区间,37.0% - -49.2%)白色的参与者(P <措施)。这组有优势比为0.51(95%可信区间,0.38 - -0.68)进行推荐与白人相比筛选过程参与者在调整了年龄、性别、教育地位、年收入、保险地位,受影响的总数和未受影响罗斯福,时间自去年医疗访问。美国人与多个罗斯福或影响50岁,之前亲戚诊断曾经经历了内窥镜检查不太可能结肠息肉(优势的个人历史报告比,0.29;与白人相似的家庭历史。结论:非裔美国人罗斯福结肠癌是不太可能发生结肠镜筛查与白人相比影响了亲戚。针对识别和管理缺医少药人群的风险增加结肠癌基于他们的家庭的历史。

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