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The relationship between fatigue and cardiac functioning.

机译:疲劳和心脏之间的关系功能。

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BACKGROUND: Although characteristics such as heart rate (HR) and blood pressure (BP) are commonly reported in studies of the relationship between fatigue and cardiac functioning, few reports examine how cardiac function parameters such as cardiac output (CO) and stroke volume (SV) relate to fatigue. This study examined the relationship between self-reported fatigue and hemodynamic functioning at rest and in response to a public speaking stressor in healthy individuals. METHODS: A total of 142 individuals participated in this study. Subjects were placed in low-, moderate-, or high-fatigue groups based on their Profile of Moods State fatigue scale. Heart rate, SV, and CO were determined using impedance cardiography at rest and during a speaking stressor. Stroke volume and CO values were converted to stroke index (SI) and cardiac index (CI) by adjusting for body surface area. Data were analyzed with hierarchical regression analysis and a 3 (group) x 3 (stress period) mixed model analysis of variance. RESULTS: At rest, fatigue was not associated with BP or HR but was significantly associated with decreased CI (P < .001; 95% confidence interval, -0.046 to -0.014) and stroke index (SI) (P = .002; 95% confidence interval -0.664 to -0.151), even after controlling for demographic variables and depressive symptoms. Heart rate and BP increased, as expected, from baseline to preparation to speaking stressor (F (1,124) = 118.6 and F (1,122) = 46.450, respectively) (P < .001 for both). More interestingly, there were effects on SI and CI of fatigue (P<.03 for both) and stress (P<.03 for both); high-fatigue individuals had lower SI and CI levels than moderate- and low-fatigue individuals both at rest and in response to the stressor. CONCLUSION: This study demonstrates that fatigue complaints may have hemodynamic correlates even in ostensibly healthy individuals.
机译:背景:虽然心等特点率(人力资源)、血压(BP)是常见的在研究之间的关系疲劳和心脏功能,很少报道检查心脏功能等参数心输出量(CO)和中风量(SV)联系起来疲劳。自我报告的疲劳和血流动力学之间的关系功能在休息和对公众的反应在健康个体的压力源。方法:共有142人参加在这项研究中。基于他们的温和,或high-fatigue组情绪状态的疲劳。SV,公司决定使用阻抗心动描记法在休息,在说话压力源。转换为中风指数(SI)和心脏指数(CI)通过调整身体表面积。和分层回归分析了吗分析和3(集团)x 3(压力)混合模型方差分析。休息,疲劳与英国石油(BP)或人力资源无关但能显著降低CI (P <措施;-0.014)和中风指数(SI) (P = .002;置信区间-0.664 - -0.151),即使对人口统计学变量和控制抑郁症状。正如所料,从基线到准备说压力源(F (1124) = 118.6, F分别为(1122)= 46.450)(P <措施两个)。SI和CI疲劳(P <。(P <。SI和CI水平低于温和的和个人在休息和疲劳对压力源的反应。表明,疲劳的投诉即使在表面上健康的血液动力学相关个人。

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