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An older man with fatigue

机译:一个疲劳的老人

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摘要

Fatigue is a common presentation with such a wide differential diagnosis that it can be difficult to streamline the workup. This challenging case is of a 76-year-old man presenting after 1 month of worsening weakness. Part of the workup focused on the patient's renal failure. Beginning with a urinalysis, a stepwise approach was used that led to exploration of a chronic, cellular-mediated autoimmune process. Ultimately a tissue diagnosis was need. Pauci-immune glomerulonephritis is a rare, treatable disease that fit our patient's profile. The specific diagnosis was essential to understand its natural history and to direct management.
机译:疲劳是一种常见的表现形式,具有广泛的鉴别诊断,可能难以简化检查工作。这个具有挑战性的案例是一名76岁的男性在1个月的无力恶化后出现。部分检查的重点是患者的肾功能衰竭。从尿液分析开始,采用了逐步方法,导致探索了一种慢性的,细胞介导的自身免疫过程。最终需要组织诊断。免疫低密度脂蛋白性肾小球肾炎是一种罕见的可治疗疾病,符合我们患者的情况。具体的诊断对于了解其自然历史和直接管理至关重要。

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