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首页> 外文期刊>BMJ: British medical journal >Commentary: Predicting and preventing premature mortality
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Commentary: Predicting and preventing premature mortality

机译:评论:预测和防止过早死亡率

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摘要

Established risk factors for premature mortality may be fixed or modifiable. Prevention in clinical practice naturally concentrates on identifying and attempting to correct modifiable factors such as smoking, hypertension, and hyperlipidaemia. In this context, fixed predictors such as age, sex, and family history of disease may be useful in guiding decisions about whom and when to treat. Under the common (but rarely tested) assumption that the relative benefits of treatment are the same for different patient groups, greater absolute benefits may be expected for patients at higher underlying risk of disease. The balance of benefits and side effects may thus depend on the level of fixed risk factors. Pharmacological treatment for mild hypertension, for instance, may be justified at a lower level of initial blood pressure among older patients or those with a family history of cardiovascular disease.
机译:建立了过早死亡的危险因素可能是固定或修改。临床实践自然集中于正确识别和试图修改因素如吸烟、高血压、和hyperlipidaemia。预测因素如年龄,性别,和家庭的历史疾病可能是有用的在指导决策谁来治疗。(但很少测试)假设相对治疗是相同的不同的好处病人组,更大的可能是绝对的好处预期对病人潜在的风险更高的疾病。因此,影响可能依赖于固定的水平风险因素。例如,高血压可能是合理的低水平的初始血压老年人当中病人或那些有家庭的历史心血管病

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