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首页> 外文期刊>Current medicinal chemistry-Anti-inflammatory & anti-allergy agents.Anti-inflammatory & anti-allergy agents >Effects of Natural Products on Contact Dermatitis
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Effects of Natural Products on Contact Dermatitis

机译：天然产物对接触性皮炎的影响

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摘要

Some medicinal plants, which are known to produce allergic reactions, are also specifically used as anti-inflammatory agents. Among the more relevant plants, we report species with cinnamaldehyde, cinnamic alcohol, geraniol, hydroxycitroncllal, eugenol and isoeugenol are all potential allergens. In addition, fragrances, which are mixtures of small-molecular-weight compounds, may induce allergic contact dermatitis due to fragrance-specific CD4~+ and CD8+ T lymphocytes. Plants from the Asteraceae family used in folk medicine as anti-inflammatories can cause allergic contact dermatitis because of its content in sesquiterpene lactones, which have been reported as the anti-inflammatory principles in this speciesSpecies with flavonoids, iridoids, terpenoids and alkaloids have been described as inhibitors of contact dermatitis. Scrophularia auriculata, Poria cocos, Santolina chamaecyparissus, Ranunculus sceleratus and Helichrysum italicum all showed activity in different experimental protocols of contact dermatitis, thus justifying the potential use of these medicinal plants as anti-allergens and inhibitors of contact dermatitis reactions produced by allergens and chemicals Hydroquinone derivatives such as l-O-beta-glucopyranosyl-2-(3'-hydroxymethyl-3'-methylallyl) hydroquinone and arbutin, flavonoids such as kaempferol, apigenin and genistein, sesquiterpene lactones such as helenalin, diterpenes such as triptonide, triterpenes such as tripterine and bryonolic acid, iridoids such as scrovalentinoside, alkaloids such as indirubin, dehydrocorydaline, magnoflorine hydroxide and phellodendrine acetate, and polysaccharides such as fucoidin have been reported as inhibitors of contact dermatitis reactions.
机译：生产一些药用植物,这是已知的过敏反应,也专门用作抗炎剂。植物,我们报告物种与肉桂醛,hydroxycitroncllal肉桂醇,香叶醇,丁香酚和异丁子香酚都是潜力过敏原。small-molecular-weight化合物的混合物,阿美诱发过敏性接触性皮炎是由于fragrance-specific CD4 ~ +和CD8 + T淋巴细胞。从菊科植物家族在民间使用药物作为抗炎药可导致因为其过敏性接触性皮炎倍半萜烯内酯含量,被报道为抗炎的原则在这个speciesSpecies类黄酮、环烯醚萜苷萜类化合物和生物碱已被描述为接触性皮炎的抑制剂。蓝花、茯苓、Santolina蜡菊italicum展示活动不同的实验协议的接触皮炎,从而证明了潜在的使用这些药用植物anti-allergens和接触性皮炎的抑制剂的反应由过敏原和化学品对苯二酚衍生品等

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