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首页> 外文期刊>Journal of endometriosis and pelvic pain disorders. >Uterus transplantation: current state and future perspectives
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Uterus transplantation: current state and future perspectives

机译：子宫移植:当前状态和未来视角

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摘要

Absolute uterine factor infertility (AUFI) has traditionally been regarded as untreatable. Gestational surrogacy (GS) is not permitted in most countries and societies in the world due to ethical, religious or legal reasons. The interest in uterus transplantation (UTx) as a treatment for AUFI started in the 1960s and, after some disappointing results, raised again in the new century, when our and other groups obtained live off-spring after UTx in the mouse, and here we review extensively the results of animal research. In September 2014, the first baby was born after human UTx and this proof-of-concept of UTx as an infertility treatment has been followed by several more births. All cases described in the literature are also reviewed.The overall evidence suggests that the clinical introduction of UTx as the first available treatment for AUFI has been successful. However, UTx will stay at experimental stage for several years whilst optimizing the procedure and ensuring its safety from a medical and psychological perspective.
机译：绝对子宫因素不孕(AUFI)传统上被认为是无法治愈的。代孕(GS)是不允许的世界上大多数国家和社会原因伦理、宗教或法律原因。在子宫移植(UTx)治疗AUFI始于1960年代,经过一些令人失望的结果,在新的复活世纪,当我们和其他团体生活后代在鼠标属下之后,这里我们动物广泛审查的结果研究。人类属下这概念验证之后出生的属下的不孕治疗之后由几个出生。文献也回顾了。证据表明,临床介绍UTx作为AUFI第一个可用的治疗已经成功。几年来虽然实验阶段优化程序,并确保它的安全从医学和心理学的角度来看。

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