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Novel coronavirus disease (COVID-19): origin, transmission through the environment, health effects, and mitigation strategies—a review

机译:新型冠状病毒病(COVID-19):起源、通过环境、传播健康效果,和缓解策略审查

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Abstract The novel coronavirus disease (COVID-19), caused by severe acute respiratory coronavirus-2 (SARS-CoV-2), was?first identified in China and?subsequently spread globally, resulting in a severe pandemic, and officially declared a significant health emergency by World Health Organization (WHO). Genetic analysis of coronavirus isolated from bats, snakes, and Malay pangolins suggested that they could be intermediate hosts for SARS-CoV-2. The transfer of virus from person to person has been confirmed widely, while the actual source of origin is still unknown. COVID-19 is a highly contagious and infectious disease, and the worldwide transmission of coronavirus has intense effects on the lives of human beings. The spread of the virus is observed mainly through close contact with the infected person due to coughing, sniffing or indirectly through the contaminated surfaces. If people touch contaminated surfaces through their hands, mouth, nose, or eye, it enters the body and causes disease. Also, the virus may transmit through air droplets, water, food, fecal–oral transmission, etc. The infection of virus in human beings could be?detected by direct symptoms, or different diagnostic tools are available to determine the viral load. Various safety measures are used to contain the virus, including disinfectants, antiviral drugs, vaccines, wearing masks, social distancing, etc. In the present review, we have focused on transmission of COVID-19 through air and wastewater as environmental transmission modes. We have also discussed the origin of the virus, its mode of action, host immune response, vulnerability, varying symptoms and diagnosis, prevention and control. Further, we have discussed the various treatment options to cope with this viral outbreak.Graphical abstract
机译:摘要新型冠状病毒病(COVID-19),严重急性呼吸系统coronavirus-2所致(SARS-CoV-2) ?然后呢?严重的流感大流行,正式宣布世界卫生重大卫生紧急状态组织(WHO)。冠状病毒与蝙蝠、蛇、和马来语穿山甲建议SARS-CoV-2中间宿主。病毒从一个人到另一个人已经得到证实广泛的,而实际的来源仍然未知。和传染病,世界范围内冠状病毒的传播有强烈的效果在人类的生活。观察到病毒主要是通过密切接触与感染者由于咳嗽,嗅探或间接污染表面。通过他们的手,嘴,鼻子,眼睛,进入人体,引起疾病。病毒可以通过空气飞沫传播,水,食物、接触传染等。的病毒在人类可以吗?直接的症状,或不同的诊断工具可用来确定病毒载量。用于包含各种安全措施病毒,包括消毒剂、抗病毒药物,疫苗,戴着面具,社会距离等。在目前的审查,我们关注通过空气和COVID-19的传播废水环境传播模式。我们还讨论了病毒的起源,其作用方式、宿主免疫反应,脆弱,不同的症状和诊断,预防和控制。讨论了各种治疗方法应对这种病毒爆发。

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