Potential key factors involved in regulating adipocyte dedifferentiation

Shiqi Liu; Liyi Wang; Defeng LingTeresa G. ValencakWenjing YouTizhong Shan

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Potential key factors involved in regulating adipocyte dedifferentiation

机译：潜在的关键因素参与调节脂肪细胞去分化

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Abstract Adipocytes are the key constituents of adipose tissue, and their de‐differentiation process has been widely observed in physiological and pathological conditions. For obese people, the promotion of adipocyte de‐differentiation or maintenance of an undifferentiated state of adipocytes may help to improve their metabolic condition. Thus, understanding the regulatory mechanisms of adipocyte de‐differentiation is necessary for treating metabolic diseases. Attractively, in addition to intracellular signals regulating adipocyte de‐differentiation, external factors such as temperature and pressure also affect adipocyte de‐differentiation. In this review, we summarize the recent progress in the field and discuss the regulatory roles and mechanisms of involved endogenous and exogenous factors during the process of de‐differentiation.

机译：抽象的脂肪细胞的主要成分是脂肪组织,de分化被广泛观察到的生理过程和病理条件。促进脂肪细胞分化或应承担的维护的一个未分化状态脂肪细胞可能有助于改善他们的代谢条件。de量脂肪细胞分化的机制必要的治疗代谢疾病。吸引力,除了细胞内de量信号调节脂肪细胞分化,外部因素如温度和压力也会影响脂肪细胞de分化。审查中,我们总结的最新进展场和监管角色和讨论内生和外生机制有关地理因素过程中de分化。

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来源
《Journal of cellular physiology.》 |2022年第3期|1639-1647|共9页
作者
Shiqi Liu; Liyi Wang; Defeng LingTeresa G. ValencakWenjing YouTizhong Shan;
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作者单位

College of Animal Sciences,Zhejiang University;

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原文格式 PDF
正文语种英语
中图分类
关键词
Adipocytes; Signal Pathways; Anaplasia;

机译：脂肪细胞、信号通路间变;

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Potential key factors involved in regulating adipocyte dedifferentiation

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