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首页> 外文期刊>Journal of cellular physiology. >An updated review of the association of host genetic factors with susceptibility and resistance to COVID-19
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An updated review of the association of host genetic factors with susceptibility and resistance to COVID-19

机译：一个更新审查协会的主机遗传因素和易感性抵抗COVID-19

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摘要

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human populations sparked a global pandemic of the coronavirus disease 2019 (COVID-19). According to preliminary data, about 14% of cases are considered severe and 5% of cases result in critical illness and, reported case fatality rates vary from 1% to more than 7%. However, the symptoms of the disease and the clinical outcome are very different in infected people. In view of these differences, it is clearly apparent that to gain insight into the biology of the SARS-CoV-2, it is important to study not just the infectious particle in itself but also to investigate the virus-host cell interactions that occur during infection. This review seeks to consider the various aspects of genetic factors in determining the susceptibility and host resistance to SARS-CoV-2 throughout the recently published literature.
机译：严重急性呼吸系统的出现综合症冠状病毒2 (SARS-CoV-2)在人类人口引发的全球大流行冠状病毒疾病2019 (COVID-19)。初步数据,大约14%的病例被认为是严重的和5%的情况下导致重要疾病,病死率利率从1%变化到7%以上。疾病的症状和临床结果在受感染的人是非常不同的。这些差异,这显然是明显的洞察SARS-CoV-2生物学,是很重要的研究不仅具有传染性粒子本身也探讨宿主细胞相互作用时产生的感染。遗传因素在确定的各个方面磁化率和宿主抵抗SARS-CoV-2整个最近出版的文学。

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