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Hyperbaric oxygen improves nasal air flow.

机译:高压氧改善鼻气流。

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OBJECTIVE: We investigated whether hyperbaric oxygen (HBO2) treatment is able to cause any changes in the nasal peak inspiratory flow (NPIF) values of patients submitted to this therapy. STUDY DESIGN: NPIF was measured in a group of 13 patients who were submitted to at least 10 sessions of 75 minutes long HBO2 treatments over a period of 20 days. HBO2 was prescribed to the patients to treat hearing loss, diabetic ulcers or chronic inflammatory disease. Three timings were chosen to perform the NPIF measurements: during HBO2, five minutes before and five minutes after the treatment. METHODS: For NPIF evaluation, the highest inspiratory flow of three inspirations was recorded. To search for statistical differences between NPIF measurements at the three different timings of the HBO2 treatment, we have analysed the data using the repeated measures ANOVA test with the Epsilon lower bound correction for the F ratio. RESULTS: NPIF values were significantly higher when the patients were inside the HBO2 chamber when compared with NPIF measurements obtained in the same individuals five minutes before starting or five minutes after ending the treatment. A small but significant increase in NPIF values was detected in patients five minutes after stopping the HBO2 treatment, in comparison with values obtained five minutes before initiating the therapy. NPIF values remained stable along the 10 HBO2 sessions, i.e. with repetition of the HBO2 treatments, NPIF values were not further enhanced. CONCLUSIONS: Exposure to HBO2 causes significant improvement in nasal air flow. This increase is restricted mostly to the period that the patients are inside the hyperbaric chamber. Further investigations are needed to determine the relative contributions of enhancement in air pressure and in oxygen concentration (that characterize HBO2) in the enhancement of nasal air flow. The herein finding may be helpful in future investigations on the treatment of nasal or sinus diseases.
机译:目的:我们研究了高压氧(HBO2)能够引起任何治疗鼻吸气流量(NPIF)峰值的变化值的患者提交这种疗法。研究设计:NPIF测量一组13患者提交至少10会话75分钟HBO2治疗结束一段时间的20天。听力损失患者治疗,糖尿病溃疡或慢性炎性疾病。选择执行NPIF测量:HBO2期间,前5分钟和5分钟后的治疗。评价最高的三个吸气流灵感被记录。统计差异NPIF测量在三种不同HBO2计时治疗时,我们使用的数据进行了分析重复测量方差分析测试与ε下界F值的修正。NPIF值时都非常的高患者在HBO2室时相比之下,NPIF测量获得的个人开始前五分钟或相同五分钟后结束治疗。但在NPIF值显著增加在病人中发现五分钟后停止HBO2治疗相比,值开始前5分钟治疗。HBO2会话,即与HBO2的重复没有进一步的治疗,NPIF值增强。显著改善鼻气流。增加限制主要的时期高压氧舱内部的病人。还需要进一步的调查来确定增强空气的相对贡献压力和氧浓度(描述HBO2)鼻的增强空气流。未来的调查在治疗鼻或鼻窦疾病。

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