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Preflight, In-Flight, and Postflight Imaging of the Cervical and Lumbar Spine in Astronauts

机译:起飞、飞行和通成像的颈椎和腰椎宇航员

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BACKGROUND: Back pain is a common complaint during spaceflight that is commonly attributed to intervertebral disc swelling inmicrogravity. Ultrasound (US) represents the only imaging modality on the International Space Station (ISS) to assess its etiology. The present study investigated: 1) The agreement and correlation of spinal US assessments as compared to RESULTS of pre- and postflight MRI studies; and 2) the trend in intervertebral disc characteristics over the course of spaceflight to ISS.METHODS: Seven ISS astronauts underwent pre- and postflight US examinations that included anterior disc height and anteriorintervertebral angles with comparison to pre- and postflight MRI RESULTS. In-flight US images were analyzed for changes in disc height and angle. Statistical analysis included repeated measures ANOVA with Bonferroni post hoc analysis, Bland-Altman plots, and Pearson correlation.RESULTS: Bland-Altman plots revealed significant disagreement between disc heights and angles for MRI and US measurements while significant Pearson correlations were found in MRI and US measurements for lumbar disc height (r~2 = 0.83) and angle (r~2 = 0.89), but not for cervical disc height (r~2 = 0.26) or angle (r~2 = 0.02). Changes in anterior intervertebral disc angle—initially increases followed by decreases—were observed in the lumbar and cervical spine over the course of the long-duration mission. The cervical spine demonstrated a loss of total disc height during in-flight assessments (~0.5 cm).DISCUSSION: Significant disagreement but significant correlation was noted between US and MRI measurements of disc height and angle. Consistency in imaging modality is important for trending measurements and more research related to US technique is required.
机译:背景:在背部疼痛是一种常见的投诉通常归因于太空飞行椎间盘肿胀inmicrogravity。超声(美国)代表唯一的成像形态在国际空间站(ISS)评估它的病因。调查:1)协议和相关的脊髓我们评估的结果相比预处理和通MRI研究;在椎间盘的特点太空飞行的国际空间站。宇航员进行了预处理和通考试,包括前片高度和anteriorintervertebral角度比较预处理和通磁共振成像结果。图像分析椎间盘高度的变化和角度。措施与Bonferroni事后分析,方差分析Bland-Altman情节,皮尔森相关性。重要的椎间盘高度和之间的分歧角度对MRI和我们测量时间重要的皮尔逊相关性被发现磁共振成像和我们测量腰椎椎间盘高度(r ~ 2 = 0.83)和角度(r ~ 2 = 0.89),但不是颈椎间盘高度(r ~ 2 = 0.26)或角(r ~ 2 =0.02)。angle-initially增加紧随其后decreases-were观察腰椎和颈椎的长期的任务。演示了一个损失在总盘的高度动态评估(~ 0.5厘米)。重大分歧但意义重大我们之间的相关性是指出,核磁共振测量阀瓣高度和角度。成像模式的一致性是很重要的相关的测量和更多的研究趋势对我们的技术是必需的。

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