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首页> 外文期刊>Aerospace medicine and human performance. >Dilated Prelaminar Paravascular Spaces as a Possible Mechanism for Optic Disc Edema in Astronauts
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Dilated Prelaminar Paravascular Spaces as a Possible Mechanism for Optic Disc Edema in Astronauts

机译：作为一个扩张Prelaminar Paravascular空间视神经盘水肿的可能机制宇航员

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INTRODUCTION: A number of ophthalmic abnormalities, including optic disc edema, have been reported in several astronauts involved in long-duration spaceflights. An increased understanding of factors contributing to this syndrome, initially designated visual impairment and intracranial pressure syndrome and recently renamed spaceflight-associated neuro-ocular syndrome, has become a high priority for ESA and NASA, especially in view of future long-duration missions, including trips to Mars. The underlying pathophysiological mechanisms of this syndrome are still not well understood. In the present paper, we propose that optic disc edema in astronauts may occur, at least in part, as a result of retention of interstitial fluid in distended paravascular spaces at the prelaminar region of the optic nerve head. Preflight, in-flight, and postflight analysis of the optic nerve head and surrounding structures by optical coherence tomography in long-duration International Space Station crewmembers could provide important structural information in this respect.
机译：简介:许多眼科异常,包括视神经盘水肿在几个宇航员参与报道长时间的太空飞行中。理解的因素综合症,最初指定的视力损害和颅内压力综合症和最近重命名spaceflight-associated neuro-ocular综合症,已经成为一个高优先级的ESA和美国国家航空航天局(NASA),特别是在未来长期的观点任务,包括去火星。这种综合症的病理生理机制仍不清楚。纸,我们提议视神经盘水肿宇航员可能发生,至少在某种程度上,作为一个保留的组织液的结果膨胀prelaminar paravascular空间视神经头部区域。空中,通视的分析周围神经的头和光学结构在长时间相干断层扫描国际空间站宇航员提供重要的结构信息尊重。

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