Equivalent Air Altitude and the Alveolar Gas Equation

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Equivalent Air Altitude and the Alveolar Gas Equation

机译：等效空气高度和肺泡气体方程

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INTRODUCTION: It is expedient to use normobaric hypoxia (NH) as a surrogate for hypobaric hypoxia (HH) for training and research.The approach matches inspired oxygen partial pressure (P(l)o(2)) at the desired altitude to that at site pressure (PB) by reducing the inspired fraction of oxygen (P(l)o(2)) to <0.21 using the equation: P(l)o(2) = (PB -47) X F(l)o(2), where 47 mmHg is the vapor pressure of water at 37 degrees C. The investigator then has at site pressure the equivalent P(l)o(2) as at altitude, i.e., the NH exposure is at an "equivalent air altitude." Some accepted as fact identical signs and symptoms of hypoxia for both conditions. However, those that derived the alveolar air equation showed that the coupled alveolar oxygen (PAO2) and carbon dioxide partial pressures (P(A)co(2)) for NH and HH are not identical when P(l)o(2) is equivalent.They attribute the difference in alveolar gas composition under equivalent P(l)o(2) to a nitrogen dilution effect or, more generally, to the respiratory exchange effect.Those that use NH as a convenient surrogate for HH must concede that physiological responses to NH cannot be identical to the responses to HH given only equivalent hypoxic P(l)o(2).

机译：作品简介:这是使用normobaric权宜之计缺氧(NH)作为低比重的缺氧的代理(HH)培训和研究。比赛激发了氧气分压(P (l) o(2)),在所需的高度网站(PB)通过减少了压力分数的氧气(P (l) o(2)) < 0.21使用方程:P (l) o (2) = -47 (PB) X F (l) o (2)47在37毫米汞柱是水的蒸汽压度c .调查员已经在网站压力相当于P (l) o(2)在高海拔处,也就是说,NH暴露在一个“等效空气高度。”条件和缺氧的症状。然而,那些派生肺泡气方程表明,耦合肺泡氧气(PAO2)和二氧化碳分压(P (A)有限公司(2))NH和HH并不相同P (l) o(2)是等价的。差异在肺泡气体成分等效P (l) o(2)氮气稀释效应或者,更普遍的是,呼吸交换的效果。代理HH必须承认生理对NH不能相同的反应对HH只有等效缺氧的反应P (l) o(2)。

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《Aerospace medicine and human performance.》 |2016年第1期|61-64|共4页
作者
Conkin Johnny;
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作者单位

Univ Space Res Assoc, Houston, TX 77058 USA;

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正文语种英语
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gas composition; PHYSIOLOGICAL RESPONSES; Vapor PressureEquivalentHypoxiaIdenticalinspired oxygen concentration;

机译：气体成分,生理反应;蒸汽PressureEquivalentHypoxiaIdenticalinspired氧气浓度;

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Equivalent Air Altitude and the Alveolar Gas Equation

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