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Andropause and the aging male.

机译:男性更年期和衰老的男性。

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摘要

For many years andropause has been compared to female climaterium. Data show that symptoms are more an identification process with the climateric partner. Sexual function decreases with age but hormonal changes are not the major determining factor in this decline. There is histological evidence of an aging testicle, with reduced number of Leydig and Sertoli cells. Testosterone also declines about a third, as do dehydroepiandrosterone, dehydroepiandrosterone sulfate, prolactin, growth hormone, and insulin growth factor-1. There is no change in dehydrotestosterone and estrogens and there is an increase in follicle stimulating and luteinizing hormones levels. Recent data cannot recommend the use of hormone replacement therapy with androgens because of potential severe side effects and lack of data on long-term effects.
机译:多年以来,男性更年期已被与女性气垫相比较。数据表明,症状更多地是与气候伙伴的识别过程。性功能随着年龄的增长而下降,但荷尔蒙的变化并不是导致这种下降的主要因素。有组织学证据表明睾丸老化,Leydig和Sertoli细胞数量减少。睾丸激素也下降了约三分之一,脱氢表雄酮,硫酸脱氢表雄酮,催乳激素,生长激素和胰岛素生长因子-1也是如此。脱氢睾丸激素和雌激素没有变化,卵泡刺激素和黄体生成素的水平也有所增加。由于潜在的严重副作用以及缺乏长期作用的数据,最近的数据不能推荐激素替代疗法与雄激素一起使用。

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