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首页> 外文期刊>Archives of Iranian medicine >Outcomes of liver transplantation for patients with acute liver failure
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Outcomes of liver transplantation for patients with acute liver failure

机译:急性肝衰竭患者肝移植的结果

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Background: Liver transplantation is a treatment for patients who have acute liver failure (ALF). This study aims to evaluate the outcomes following liver transplantation in patients with ALF and compare them with cirrhotic patients who underwent liver transplantation. Methods: This retrospective cross-sectional study was conducted at Shiraz Organ Transplant Center between June 2004 and March 2011 to evaluate the clinical presentation and underlying etiology of patients with ALF and their outcomes following liver transplantation. Results: Out of 750 patients who underwent liver transplants, 12 (8 males and 4 females) had a diagnosis of ALF. The cirrhotic group (control) consisted of 20 transplanted patients. ALF patients were younger with a mean age of 18.7 ± 12.9 years compared to 37.4 ± 13.6 years in the cirrhotic group (P = 0.001). In the ALF group, 5 (41.66%) underwent partial living related liver transplantation compared to 1 (5%) in the cirrhotic group (P = 0.018). There were significantly more early post-transplant complications observed among patients with ALF compared to the cirrhotic group (P = 0.002). Conclusion: Liver transplantation is safe, effective and should be considered in patients diagnosed with ALF.
机译:背景:肝移植是急性肝衰竭(ALF)患者的治疗方法。这项研究旨在评估ALF患者肝移植后的结局,并将其与接受肝移植的肝硬化患者进行比较。方法:这项回顾性横断面研究于2004年6月至2011年3月在设拉子器官移植中心进行,以评估ALF患者的临床表现和潜在病因以及肝移植后的结局。结果:在接受肝移植的750例患者中,有12例(男性8例,女性4例)被诊断为ALF。肝硬化组(对照组)由20例移植患者组成。 ALF患者较年轻,平均年龄为18.7±12.9岁,而肝硬化组为37.4±13.6岁(P = 0.001)。在ALF组,有5例(41.66%)进行了部分生活相关的肝移植,而在肝硬化组中有1例(5%)(P = 0.018)。与肝硬化组相比,ALF患者的移植后早期并发症要多得多(P = 0.002)。结论:肝移植术安全,有效,ALF患者应考虑肝移植。

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