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首页> 外文期刊>Head and neck: Journal for the sciences and specialities of the head and neck >Intraoperative evaluation of bony margins with frozen-section analysis and trephine drill extraction technique: A preliminary study.
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Intraoperative evaluation of bony margins with frozen-section analysis and trephine drill extraction technique: A preliminary study.

机译：术中评估骨边缘冰冻切片分析和环钻钻提取技术:一项初步研究。

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摘要

BACKGROUND: The aim of this study was to examine the use of trephine drill specimens from mandible bony margins subjected to standard histologic fresh-frozen processing for intraoperative documentation of malignant bony infiltration in oral cancer. METHODS: Eighty-four drill specimens were extracted from bony mandibular resection margins of 20 patients with oral cancer. Histologic results of decalcification and of intraoperative frozen-section analysis were compared. RESULTS: Sixty-eight (81%) of 84 specimens showed no tumor infiltration, whereas 16 (19%) were positive in frozen section analysis. Four specimens (4.8%) were evaluated as free of tumor invasion, but showed erosion of the bone by the tumor after decalcification. One specimen (2.4%) was positive, but no invasion could be found with standard decalcification. Overall, there was 94% (79) consistency between the 2 techniques, with a sensitivity of 79% and specificity of 98%. CONCLUSION: This technique promises to be suitable for intraoperative detection of malignant bone infiltration.
机译：背景:本研究的目的是检查环钻钻下颌骨标本的使用骨边缘受到标准的组织学用来处理术中文档的恶性骨渗透口腔癌。从骨下颌切除吗20口腔癌患者的利润率。脱钙作用和组织学结果术中冰冻切片分析比较。标本显示没有肿瘤浸润,而16(19%)在冰冻切片是积极的分析。免费的肿瘤的入侵,但显示的侵蚀骨脱钙作用后的肿瘤。标本(2.4%)是积极的,但没有入侵能找到与标准脱钙作用。总体而言,有94%(79)之间的一致性2技术,灵敏度为79%特异性为98%。有望成为适合术中检测恶性骨渗透。

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