Nonanuclear coordination complex based on {Co_9L_(12)}~(6+) cores: protective effect on coronary heart disease by reducing the inflammatory cytokines releasing

Fengquan Dong; Weipeng Jiang; Yajuan JiangXiaozheng LiHaiying Li

首页> 外文期刊>Chemical papers >Nonanuclear coordination complex based on {Co_9L_(12)}~(6+) cores: protective effect on coronary heart disease by reducing the inflammatory cytokines releasing

【24h】

Nonanuclear coordination complex based on {Co_9L_(12)}~(6+) cores: protective effect on coronary heart disease by reducing the inflammatory cytokines releasing

机译：Nonanuclear协调复杂的基于{Co_9L_(12)} ~(6 +)核心:保护作用冠心病通过减少炎性细胞因子释放

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A new coordination complex with the chemical formula of [ Co_9(bta)_(12)(NO_3)_6(DMA)_6]·3DMA (1), (DMA = N,N-dimethylacetamide) was formed by solvothermal reaction of Co(NO_3)_2·6H_2O with Hbta (Hbta = benzotriazole). The as-prepared complex 1 was characterized via thermogravimetric (TG) analysis, analysis of element, X-ray single-crystal diffraction, and powder X-ray diffraction (PXRD). Furthermore, the treatment activity of the compound on the Coronary atherosclerotic heart disease (CHD) was assessed and mechanism was investigated at the same time. First, the release of inflammatory cytokines in plasma was detected by enzyme linked immunosorbent assay (ELISA) test kit. Then, the real time reverse transcriptionpolymerase chain reaction (RT-PCR) was finished to determine the tumor necrosis factor-a induced protein-8 type2 (TIPE2) expression levels in endothelial cells. The molecular docking results reveal the possible interacting poses for the potential capability of immune homeostasis.

机译：一个新的协调复杂的化学物质公式(Co_9 (bta) _ (12) (NO_3) _6 (DMA) _6]·3 DMA(1), (DMA = N, N-dimethylacetamide)成立solvothermal反应公司(NO_3) _2·h_2o 6Hbta (Hbta =苯并三唑)。通过热重复杂1为特征(TG)分析、元素分析、x射线单晶衍射和粉末x射线衍射(PXRD)。冠状的化合物的活性动脉粥样硬化性心脏病(冠心病)是评估同时和机制研究。首先,炎性细胞因子的释放等离子体是由酶联检测到的免疫吸附试验(ELISA)检测组件。实时反向transcriptionpolymerase链反应(rt - pcr)是确定完成肿瘤坏死因子a诱导protein-8 type2(TIPE2)内皮细胞的表达水平。分子对接结果揭示的可能相互作用构成的潜在能力免疫内稳态。

著录项

来源
《Chemical papers》 |2021年第4期|1355-1362|共8页
作者
Fengquan Dong; Weipeng Jiang; Yajuan JiangXiaozheng LiHaiying Li;
展开▼
作者单位

Department of Cardiology, Shenzhen University General Hospital, Shenzhen, Guangdong, China;

College of Life Science and Oceanography, Shenzhen University, Shenzhen, Guangdong, China;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类
关键词
Coordination compounds; molecular docking; Chemical formulacrystal structureCoronary Artery DiseaseHeart Diseases;

机译：协调的化合物,分子对接;化学formulacrystal structureCoronary动脉相关的疾病;

相似文献

外文文献

1. Effects of folic acid and vitamin B12 adjuvant therapy on serum inflammatory cytokines, Hcy and NT-proBNP in elderly patients with coronary heart disease and chronic heart failure [J] . Ling-Zhi Dou, Yi-Gang Zhang, Qiu-Mei Cao, 海南医科大学学报（英文版） . 2017,第13期
2. Effects of folic acid and vitamin B12 adjuvant therapy on serum inflammatory cytokines, Hcy and NT-proBNP in elderly patients with coronary heart disease and chronic heart failure [J] . Ling-Zhi Dou, Yi-Gang Zhang, Qiu-Mei Cao, 海南医科大学学报(英文版) . 2017,第013期
3. Effects of telmisartan combined with nifedipine controlled release tablet on inflammatory factors, vascular endothelial function and left ventricular function in patients with coronary heart disease with mild to moderate hypertension [J] . Feng Guo, Bao-Wei Zhang, Zheng-Yan Zhu 海南医科大学学报（英文版） . 2017,第20期
4. Effects of telmisartan combined with nifedipine controlled release tablet on inflammatory factors, vascular endothelial function and left ventricular function in patients with coronary heart disease with mild to moderate hypertension [J] . Feng Guo, Bao-Wei Zhang, Zheng-Yan Zhu 海南医科大学学报(英文版) . 2017,第020期
5. Correlation of coronary CTA calcification score with serum inflammatory factors and plaque stability-related indexes in patients with coronary heart disease [J] . Shao-Jin Zhang, Cheng Tang, Hong Chen, 海南医科大学学报（英文版） . 2018,第4期
6. A fluorescent Zn(II)-based complex for the selective detection of PA and treatment effect on uveitis by reducing the inflammatory response and inflammatory cytokine release [J] . Chen Xuan, Liu Jian, Zhang Xin Journal of the Iranian Chemical Society . 2021,第2期

机译：A fluorescent Zn(II)-based complex for the selective detection of PA and treatment effect on uveitis by reducing the inflammatory response and inflammatory cytokine release
7. The evidence-based Mediterranean diet reduces coronary heart disease risk, and plant-derived monounsaturated fats may reduce coronary heart disease risk. [J] . Roehm E The American journal of clinical nutrition. . 2009,第3期

机译：The evidence-based Mediterranean diet reduces coronary heart disease risk, and plant-derived monounsaturated fats may reduce coronary heart disease risk.
8. The interplay of long noncoding RNA HULC with microRNA-128-3p and their correlations with lipid level, stenosis degree, inflammatory cytokines, and cell adhesion molecules in coronary heart disease patients [J] . Zhu Xuting, Hu Jun, Xie Lianhong Irish journal of medical science . 2022,第6期

机译：The interplay of long noncoding RNA HULC with microRNA-128-3p and their correlations with lipid level, stenosis degree, inflammatory cytokines, and cell adhesion molecules in coronary heart disease patients

Nonanuclear coordination complex based on {Co_9L_(12)}~(6+) cores: protective effect on coronary heart disease by reducing the inflammatory cytokines releasing

摘要

著录项

相似文献

相关主题

期刊订阅