Family history and breast cancer

June C. Carroll; Ruth Heisey; Ellen Warner

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Family history and breast cancer

机译：家族病史和乳腺癌

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摘要

Look for families with multiple cases of breast cancer or at least two relatives on the same side of the family (maternal or paternal) who had breast cancer before 50 years of age, or any case of ovarian cancer, bilateral breast cancer or breast cancer in a man.1 Breast cancer before 60 years of age in women of Ashkenazi Jewish descent also suggests increased risk.1 If the criteria for genetic testing are met,1 family members who have had cancer are tested first. If a BRCA1 or BRCA2 mutation is found, testing can be offered to unaffected relatives. Criteria for genetic testing vary across Canada - consult your local genetics clinic.

机译：寻找有多例乳腺癌的家庭癌症或至少两个亲戚在同一边的家庭(母亲或父亲的)乳腺癌在50岁之前,或任何情况下乳腺癌或卵巢癌,两国man.1乳腺癌岁女性的德系犹太人的后裔还建议增加risk.1基因检测,1家庭成员有癌症进行测试。找到BRCA2突变,测试可以提供不受影响的亲戚。测试不同加拿大咨询你当地的遗传学诊所。

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来源
《Canadian Medical Association Journal: Journal de l'Association Medicale Canadienne》 |2012年第12期|1391-1391|共1页
作者
June C. Carroll; Ruth Heisey; Ellen Warner;
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作者单位

Department of Family and Community Medicine (Carroll, Heisey), University of Toronto;

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收录信息
原文格式 PDF
正文语种英语
中图分类医药、卫生;
关键词
BRCA2 Mutation; BRCA1 Protein; Genealogical TreeFamily Membersbilateral breast cancerBreast CancerGenetic Testingfamily;

机译：BRCA2突变;BRCA1蛋白;系谱TreeFamily Membersbilateral乳房cancerBreastCancerGenetic Testingfamily;

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Family history and breast cancer

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