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首页> 外文期刊>Canadian Medical Association Journal: Journal de l'Association Medicale Canadienne >Influence of relative age on diagnosis and treatment of attention-deficit/hyperactivity disorder in children
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Influence of relative age on diagnosis and treatment of attention-deficit/hyperactivity disorder in children

机译:年龄对诊断和相对的影响治疗注意缺陷/多动障碍儿童

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Background: The annual cut-off date of birth for entry to school in British Columbia, Canada, is Dec. 31. Thus, children born in December are typically the youngest in their grade. We sought to determine the influence of relative age within a grade on the diagnosis and pharmacologic treatment of attention-deficit/ hyperactivity disorder (ADHD) in children. Methods: We conducted a cohort study involving 937 943 children in British Columbia who were 6-12 years of age at any time between Dec. 1, 1997, and Nov. 30, 2008. We calculated the absolute and relative risk of receiving a diagnosis of ADHD and of receiving a prescription for a medication used to treat ADHD (i.e., methylphenidate, dextroamphetamine, mixed amphetamine salts or atomoxetine) for children born in December compared with children born in January. Results: Boys who were born in December were 30% more likely (relative risk [RR] 1.30, 95% confidence interval [CI] 1.23-1.37) to receive a diagnosis of ADHD than boys born in January. Girls born in December were 70% more likely (RR 1.70, 95% CI 1.53-1.88) to receive a diagnosis of ADHD than girls born in January. Similarly, boys were 41% more likely (RR 1.41, 95% CI 1.33-1.50) and girls 77% more likely (RR 1.77, 95% CI 1.57-2.00) to be given a prescription for a medication to treat ADHD if they were born in December than if they were born in January. Interpretation: The results of our analyses show a relative-age effect in the diagnosis and treatment of ADHD in children aged 6-12 years in British Columbia. These findings raise concerns about the potential harms of overdiagnosis and overprescribing. These harms include adverse effects on sleep, appetite and growth, in addition to increased risk of cardiovascular events.
机译:背景:年度截止日期出生的进入学校在不列颠哥伦比亚,加拿大12月31日。通常在他们的年级最小的。确定内相对年龄的影响一年级的诊断和药物治疗注意缺陷/多动障碍(ADHD)儿童。进行了一项涉及937 943的队列研究孩子在不列颠哥伦比亚人6 - 12年之间的年龄在任何时间12月1日,1997年11月。30日,2008年。接受ADHD的诊断和风险收到一个处方药物使用治疗多动症(如哌醋甲酯,右旋安非他命,安非他命盐或混合以1)在12月出生的孩子相比之下,今年1月份出生的孩子。男孩出生在12月高出30%可能(相对危险度(RR) 1.30, 95%的信心时间间隔(CI) 1.23 - -1.37)获得诊断多动症的男孩出生在1月。12月是70%更有可能(相对危险度1.70,95%可信区间1.53 - -1.88)接受ADHD的诊断女孩出生在1月。更有可能(相对危险度1.41,95%可信区间1.33 - -1.50)和女孩77%的可能性更大(相对危险度1.77,95%可信区间1.57 - -2.00)给定一个处方药物的治疗多动症比如果他们如果他们出生在12月1月份出生。我们的分析显示的相对时代的影响儿童多动症的诊断和治疗6 - 12年的不列颠哥伦比亚省。提高潜在危害的担忧过度诊断和开抗生素。包括影响睡眠、食欲和增长,除了风险增加心血管事件。

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