首页> 外文期刊>Ophthalmologica: International Journal of Ophthalmology=Journal International d'Ophtalmologie >Retinal nerve fiber layer images captured by GDx-VCC in early diagnosis of glaucoma.
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Retinal nerve fiber layer images captured by GDx-VCC in early diagnosis of glaucoma.

机译:视网膜神经纤维层图像捕捉到GDx-VCC青光眼的早期诊断。

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摘要

OBJECTIVES: To compare differences in retinal nerve fiber layer (RNFL) parameters between normal subjects and patients with various degrees of glaucoma, evaluate the sensitivity and specificity of GDx-VCC parameters, and determine the capability of GDx-VCC parameters and the most valuable indicators for the diagnosis of early glaucoma. METHODS: GDx-VCC was used to measure RNFL in 80 patients with early glaucoma (130 eyes), 70 patients with advanced glaucoma (90 eyes) and 40 normal controls (80 eyes). All glaucoma patients were divided into an early glaucoma group and an advanced glaucoma group, according to the mean defect of the visual field. RNFL parameters were compared between normal subjects and patients with various degrees of glaucoma. Receiver operating characteristic (ROC) curves of GDx parameters were drawn to determine the most valuable GDx parameters for the diagnosis of early glaucoma. RESULTS: The RNFLs were significantly thinner in patients with early glaucoma than those in normal subjects; they were also significantly thinner in patients with advanced glaucoma than those in patients with early glaucoma. The differences in all parameters reached statistical significance (p 0.7 for all parameters, which could effectively differentiate early glaucoma from normal subjects. The areas under the ROC curves were 0.81 for nerve fiber indicator and inferior average with better differentiation capability. CONCLUSIONS: GDx-VCC can provide quantitative measurements of RNFL thickness for clinical use, which can effectively differentiate patients with early glaucoma from normal subjects, and will be clinically very helpful for the early diagnosis of glaucoma. Nerve fiber indicator and inferior average are the most effective indicators for the early diagnosis of glaucoma.
机译:目的:比较视网膜上的差异神经纤维层(RNFL)参数之间正常人和患者不同程度青光眼,评估敏感性和特异性GDx-VCC参数,并确定GDx-VCC参数和最的能力早期的诊断有价值的指标青光眼。80年RNFL早期青光眼患者(130眼睛),70晚期青光眼患者(90眼睛40)和正常对照组(80眼)。青光眼患者分为早期青光眼组和一个先进的青光眼组,根据平均视野的缺损。RNFL参数之间的比较正常主题和不同程度的患者青光眼。股票指数型基金(简称eft参数曲线来确定股票指数型基金最有价值的简称eft参数早期青光眼的诊断。早期患者明显更薄青光眼比正常人;在患者也明显更薄先进的青光眼患者比早期青光眼。达到统计学意义(p 0.7参数,可以有效的区分从正常人早期青光眼。0.81在ROC曲线下神经纤维伪劣平均有更好的指标分化能力。可以提供定量的测量RNFL吗厚度为临床使用,可有效区分早期青光眼患者正常的话题,并将临床非常对青光眼的早期诊断。神经纤维伪劣平均指标最有效的早期指标青光眼的诊断。

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