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首页> 外文期刊>Ophthalmologica: International Journal of Ophthalmology=Journal International d'Ophtalmologie >A comparative study of bimatoprost and travoprost: effect on intraocular pressure and ocular circulation in newly diagnosed glaucoma patients.
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A comparative study of bimatoprost and travoprost: effect on intraocular pressure and ocular circulation in newly diagnosed glaucoma patients.

机译：bimatoprost和travoprost的比较研究:影响眼压和眼在新诊断青光眼患者循环。

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摘要

BACKGROUND: This study compares intraocular pressure (IOP)-lowering efficacy and retrobulbar hemodynamic effects of bimatoprost and travoprost in patients with newly diagnosed open-angle glaucoma. METHODS: Patients were randomly assigned to one of two treatment groups (bimatoprost group, n = 36; travoprost group, n = 46). IOP levels were measured with Goldmann applanation tonometer. Peak systolic velocity, end-diastolic velocity and resistivity index were obtained for each vessel by color Doppler imaging. RESULTS: Both bimatoprost and travoprost significantly lowered IOP on days 30, 90 and 180 (p < 0.001). There was no significance between the 2 drugs on all follow-up visits. End-diastolic velocity of central retinal artery on day 180 was significantly higher than the value obtained at baseline in both groups. CONCLUSIONS: Patients were likely to achieve and maintain low target IOP with both drugs. Both drugs also resulted in improvement in the central retinal artery blood flow.
机译：背景:本研究比较了眼内压(IOP)降低疗效和眼球后的bimatoprost和travoprost血流动力学的影响新诊断的患者开角青光眼。分配给两个治疗组(bimatoprost组,n = 36;46)。压平式眼压计。舒张速度和电阻率指数获得由彩色多普勒为每个容器成像。显著降低眼压在30天,90年和180年(p < 0.001)。2药物在所有后续访问。视网膜中央动脉舒张速度180年天显著高于获得的价值在两组的基线。结论:患者可能达到和与这两种药物保持低目标眼压。药物也导致中央的改善视网膜动脉血液流动。

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