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首页> 外文期刊>BMJ: British medical journal >Thyroid autoantibodies, preterm birth, and miscarriage The association is clear, but the effects of levothyroxine treatment are uncertain
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Thyroid autoantibodies, preterm birth, and miscarriage The association is clear, but the effects of levothyroxine treatment are uncertain

机译:甲状腺自身抗体,早产,流产协会是清楚的,但左旋甲状腺素治疗的影响不确定

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In the linked systematic review Thangatatinam and colleagues assess the association of thyroid autoantibodies with miscarriage and preterm birth in biochemically euthyroid women and the effect of levothyroxine treatment on pregnancy outcomes. An association between thyroid antibodies and miscarriage was first reported in 1990.2 The finding was serendipitous-the prospective study was originally designed to evaluate the incidence and causes of postpartum thyroiditis. As the study progressed, the unexpected number of spontaneous miscarriages in euthyroid women with thyroid antibodies prompted the researchers to assess pregnancy outcome in the 552 women who were initially screened in the first trimester. The rate of miscarriage in thyroid antibody positive women was twice that seen in thyroid antibody negative women (17.0% v 8.4%; P=0.01).
机译:在系统回顾Thangatatinam和有关同事评估甲状腺协会自身抗体与流产和早产在生化euthyroid妇女和效果左旋甲状腺素治疗对妊娠结局。和甲状腺抗体之间有一定的联系流产在1990.2的首次报道发现serendipitous-the前瞻性研究最初是用来评估发病率和产后甲状腺炎的原因。研究进展,意想不到的数量在euthyroid女性自发流产甲状腺抗体促使研究人员评估552名女性怀孕的结果最初在妊娠前三个月的筛选。甲状腺抗体的流产率甲状腺积极的女性的两倍抗体阴性的妇女(17.0% v 8.4%;

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