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首页> 外文期刊>BMJ: British medical journal >Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis
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Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis

机译:粪便calprotectin患者的筛查怀疑炎症性肠病:诊断荟萃分析

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STUDY QUESTION Is testing stools for faecal calprotectin useful in the investigation of suspected inflammatory bowel disease?SUMMARY ANSWER Screening with a faecal calprotectin test was sensitive and specific and reduced the number of unnecessary endoscopic procedures in both adults and children and teenagers with suspected inflammatory bowel disease, but also delayed diagnosis in a small proportion.WHAT IS KNOWN AND WHATTHIS PAPER ADDS Faecal calprotectin is a sensitive marker of intestinal inflammation. An increased level of faecal calprotectin identifies those patients who are most likely to have inflammatory bowel disease and justifies urgency for endoscopy.Selection criteria for studiesWe searched Medline and Embase up to October 2009 for diagnostic accuracy studies that compared faecal calprotectin (index test) with endoscopy (reference standard). The meta-analysis included studies that had collected data prospectively in patients with suspected inflammatory bowel disease and allowed for construction of a two by two table.
机译:研究问题是测试凳子粪便calprotectin有用的调查怀疑炎症性肠病?答案与粪便calprotectin测试筛选是敏感的和具体的,减少了号码吗不必要的内镜程序在两种成人和儿童和青少年与怀疑炎症性肠病,也推迟了诊断的一小部分。WHATTHIS纸粪便calprotectin是补充道敏感的肠道炎症的标志。增加粪便calprotectin标识的水平那些最有可能的病人炎症性肠病和证明的紧迫性内窥镜检查。搜索Medline和Embase 2009年10月为诊断准确性的研究比较粪便calprotectin与内镜(指数测试)(参考标准)。研究收集数据的前瞻性患者怀疑炎症性肠疾病和允许建设的两个两个表。

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