Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial

Kenneth A Holroyd; Constance K Cottrell; Frank J ODonnellGary E Cord ingleyJana B DrewBruce W CarlsonUna Himawan

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Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial

机译：预防(β-受体阻滞药)治疗的效果,偏头痛行为管理,或他们的组合优化的结果严重治疗偏头痛频繁:随机对照试验

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STUDY QUESTION Does preventive treatment (p blocker), brief behavioural therapy (behavioural migraine management), ortheir combination improve the outcomes of an optimised acute migraine drug regimen in frequent migraine? SUMMARY ANSWER The combined treatment, but not individual treatments alone, improved the outcomes of the optimised acute treatment regimen. WHAT IS KNOWN AND WHATTHIS STUDY ADDS Preventive drugtreatment and behavioural management each seem to yield moderate improvements in migraines, but their benefits remain unclearwhen they are administered with contemporary acute migraine treatment. Only the combination of preventive drugtreatment and brief behavioural management improved outcomes compared with optimised acute treatment.

机译：研究问题并预防治疗(p拦截器),短暂的行为疗法(行为改善偏头痛管理),ortheir组合一种优化急性偏头痛药物的结果在频繁的偏头痛方案吗?综合治疗,但不是个人治疗孤独,改进优化的结果急性治疗方案。WHATTHIS研究预防drugtreatment和补充道行为管理似乎每个产量适度的改善偏头痛,但他们的好处仍unclearwhen管理与现代急性偏头痛治疗。预防drugtreatment和的结合短暂的行为管理改善的结果相比之下,优化急性治疗。

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来源
《BMJ: British medical journal》 |2010年第7776期|769-769|共1页
作者
Kenneth A Holroyd; Constance K Cottrell; Frank J ODonnellGary E Cord ingleyJana B DrewBruce W CarlsonUna Himawan;
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作者单位

225 Porter Hall, Athens, OH 45701, USA;

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原文格式 PDF
正文语种英语
中图分类医药、卫生;
关键词
Poisoning by beta-adrenergic blocking drug; Randomized Controlled Trial; Adrenergic beta-AntagonistsCombined Modality Therapybeta-blocker overdoseMigraine DisordersTreatment RegimenBehaviouralAcute;

机译：中毒的该项阻塞药物;随机对照试验;肾上腺素beta-AntagonistsCombined形态Therapybeta-blocker overdoseMigraineDisordersTreatment RegimenBehaviouralAcute;

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2. Efficacy of Zolmitriptan at Early Time-Points for the Acute Treatment of Migraine and Treatment of RecurrenceA Randomised, Placebo-Controlled Trial [J] . Robert E. Ryan, Seymour Diamond, Rose A. GiammarcoSheena K. AuroraRonald C. ReedPamela E. Fletcher cns drugs . 2000,第3期

机译：Efficacy of Zolmitriptan at Early Time-Points for the Acute Treatment of Migraine and Treatment of RecurrenceA Randomised, Placebo-Controlled Trial
3. Atogepant for the preventive treatment of chronic migraine (PROGRESS): a randomised, double-blind, placebo-controlled, phase 3 trial [J] . Pozo-Rosich P., Ailani J., Ashina M.Goadsby P.J.Lipton R.B.Reuter U.Guo H.Schwefel B.Lu K.Boinpally R.Miceli R.De Abreu Ferreira R.McCusker E.Yu S.Y.Severt L.Finnegan M.Trugman J.M. The Lancet . 2023,第10404期

机译：Atogepant for the preventive treatment of chronic migraine (PROGRESS): a randomised, double-blind, placebo-controlled, phase 3 trial
4. Safety and efficacy of eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures (DELIVER): a multi-arm, randomised, double-blind, placebo-controlled, phase 3b trial [J] . Ashina M., Lanteri-Minet M., Pozo-Rosich P.Ettrup A.Christoffersen C.L.Josiassen M.K.Phul R.Sperling B. Lancet Neurology . 2022,第7期

机译：Safety and efficacy of eptinezumab for migraine prevention in patients with two-to-four previous preventive treatment failures (DELIVER): a multi-arm, randomised, double-blind, placebo-controlled, phase 3b trial

Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimised acute treatment in frequent migraine: randomised controlled trial

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